ID A0A7K8EFI9_LEURO Unreviewed; 734 AA.
AC A0A7K8EFI9;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 10-JUN-2026, entry version 18.
DE SubName: Full=GLIS1 protein {ECO:0000313|EMBL:NXB50303.1};
DE Flags: Fragment;
GN Name=Glis1 {ECO:0000313|EMBL:NXB50303.1};
GN ORFNames=LEUROT_R03730 {ECO:0000313|EMBL:NXB50303.1};
OS Leucopsar rothschildi (Bali myna) (Rothschild's mynah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sturnidae; Leucopsar.
OX NCBI_TaxID=127929 {ECO:0000313|EMBL:NXB50303.1, ECO:0000313|Proteomes:UP000522331};
RN [1] {ECO:0000313|EMBL:NXB50303.1, ECO:0000313|Proteomes:UP000522331}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-02 {ECO:0000313|EMBL:NXB50303.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXB50303.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GLI C2H2-type zinc-finger protein family.
CC {ECO:0000256|ARBA:ARBA00010831}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXB50303.1}.
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DR EMBL; VZTC01006639; NXB50303.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8EFI9; -.
DR Proteomes; UP000522331; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-KW.
DR FunFam; 3.30.160.60:FF:000019; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000031; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000036; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000048; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000453; GLIS family zinc finger 3; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR043359; GLI-like.
DR InterPro; IPR048420; Zap1-like_Znf1.
DR InterPro; IPR056436; Znf-C2H2_ZIC1-5/GLI1-3-like.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45718; TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS; 1.
DR PANTHER; PTHR45718:SF3; ZINC FINGER PROTEIN GLIS1; 1.
DR Pfam; PF21816; Zap1_zf1; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF23561; zf-C2H2_15; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000522331};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 316..346
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 350..382
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 383..412
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 413..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 443..472
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 213..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 522..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..236
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..635
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXB50303.1"
FT NON_TER 734
FT /evidence="ECO:0000313|EMBL:NXB50303.1"
SQ SEQUENCE 734 AA; 80500 MW; 97343D99C124B7E7 CRC64;
VNGGYNHCSL ISEKKSMMDM EMPSGSVPVC RQGLFLHAGN SLVRDHALSR ERLLHVGQLN
LAHSDLRFQD SVDSAAPCLN GSHPAQHIKQ ECPSDYKVLS EASTHRRITE GMELRASGSL
HPELDLMNNS FTNSLSSYLF NNEHSSSLGP LSLGTPQHSA RLQTGNLKKR CISVVPSSAE
GIDITAIIRT SQTSLVTCVN GLRTNSAGIS SHPVEISHHS AQKSSQPQSC SQPGNPCSIP
SPPACLKVSF LKQEPADDYS STADLFRHHQ GLPPPYHLHQ QLSQTPGTLP HLSASMSPKS
LQPSDGDEQE LSSGKQVCQW IDCSATYDQQ DELVRHIEKT HIDQRKGEDF TCFWAGCVRR
YKPFNARYKL LIHMRVHSGE KPNKCMFEGC NKAFSRLENL KIHLRSHTGE KPYLCQHPGC
QKAFSNSSDR AKHQRTHLDT KPYACQIPGC SKRYTDPSSL RKHVKAHSAK EQQVRKKLKS
CTDIEQDVLS ECLAIQQLHT SSQHILDGKC GRSVGPHDLI TGMYSGSSTN HNGSSPAVLP
PPHDIPSRHL PLDSALSSPH QHQSPLESAR DGLAPNIISP LVSPLKALVP PSLLQKHGSP
SSHSQSPNGQ QFSGIPNTPY APFPNQSVQQ GSQGYQGSFH SIQNCFHYGD CYRTMDQSVS
SDVLTGESHC FNPLRQNGYH ILNAPLASAG YEGISEAQCV SEDMVSSGTD ENGFFQNSAF
DHCLNHIPSI YTDT
//
