ID A0A7K8G8Y4_ORTSP Unreviewed; 322 AA.
AC A0A7K8G8Y4;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
DE Flags: Fragment;
GN Name=Bbs5 {ECO:0000313|EMBL:NXC00811.1};
GN ORFNames=ORTSPA_R00514 {ECO:0000313|EMBL:NXC00811.1};
OS Orthonyx spaldingii (Chowchilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Corvoidea; Orthonychidae; Orthonyx.
OX NCBI_TaxID=38397 {ECO:0000313|EMBL:NXC00811.1, ECO:0000313|Proteomes:UP000526602};
RN [1] {ECO:0000313|EMBL:NXC00811.1, ECO:0000313|Proteomes:UP000526602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-029-32 {ECO:0000313|EMBL:NXC00811.1};
RC TISSUE=Liver or heart {ECO:0000313|EMBL:NXC00811.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXC00811.1}.
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DR EMBL; VZTJ01001437; NXC00811.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8G8Y4; -.
DR Proteomes; UP000526602; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR CDD; cd00900; PH-like; 1.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000526602}.
FT DOMAIN 9..63
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 139..193
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXC00811.1"
FT NON_TER 322
FT /evidence="ECO:0000313|EMBL:NXC00811.1"
SQ SEQUENCE 322 AA; 36800 MW; D1737133BECE1D28 CRC64;
RQMKMRPGEV LIDCLESVED TKGNNGDRGR LLVTNLRIIW RSLSLPRVNL SVGYNCVINI
TTRTANSKLR GQTEALYILT KCNNTRFEFI FTNVVPGSPR LFTSVIAVHR AYETSKMYRD
LKLRSALIQN KQLRLLPQEQ IYDKVNGVWN LSSDQGNLGT FFITNVRIVW HANMNDSFNV
SIPYLQIRSI KMRDSKFGLA LVIESSQQSG GYVLGFKIDP VEKLREAVTE INSLHKVYSA
NPIFGVDYEM EEKPQPLEDL TVEQVPDDVE IESDEHTDAF VAYFADENKQ HDREPVFSEE
LGLAIEKLKD GFTLQGLWEV MT
//
