ID A0A7K8JRK2_9AVES Unreviewed; 348 AA.
AC A0A7K8JRK2;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
DE Flags: Fragment;
GN Name=Bbs5 {ECO:0000313|EMBL:NXE07438.1};
GN ORFNames=LOPRUF_R04856 {ECO:0000313|EMBL:NXE07438.1};
OS Lophotis ruficrista.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Otidimorphae; Otidiformes;
OC Otididae; Lophotis.
OX NCBI_TaxID=172689 {ECO:0000313|EMBL:NXE07438.1, ECO:0000313|Proteomes:UP000533896};
RN [1] {ECO:0000313|EMBL:NXE07438.1, ECO:0000313|Proteomes:UP000533896}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-CU-031-23 {ECO:0000313|EMBL:NXE07438.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXE07438.1}.
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DR EMBL; VWYV01000190; NXE07438.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8JRK2; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000533896; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR CDD; cd00900; PH-like; 1.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000533896}.
FT DOMAIN 29..83
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 159..213
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXE07438.1"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:NXE07438.1"
SQ SEQUENCE 348 AA; 39877 MW; B5E8B4EA93820DF4 CRC64;
MSAVLDVLWE DRDVRFDVSP QQMKMRPGEV LIDCLESVED TKGNNGDRGR LLVTNLRIIW
RSLSLPRVNL SVGYNCVINI TTRTANSKLR GQTEALYILT KCNNTRFEFI FTNVVPGSPR
LFTSVIAVHR AYETSKMYRD LKLRSALIQN KQLRLLPQEQ IYDKINGVWN LSSDQGNLGT
FFITNVRIVW HANMNDSFNV SIPYLQIRSI KIRDSKFGLA LVIESSQQSG GYVLGFKIDP
VEKLQEAVKE INSLHRVYSA NPIFGVDYEM EEKPQPLEDL TVEQVQDDVE IESDEHTDAF
FLPLYFFSYL VHSNKQHDGE PVFSEELGLA IEKLKDGFTL QGLWEVMT
//
