ID A0A7K8L7Y4_9AVES Unreviewed; 456 AA.
AC A0A7K8L7Y4;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE SubName: Full=CRDL1 protein {ECO:0000313|EMBL:NXE24583.1};
DE Flags: Fragment;
GN Name=Chrdl1 {ECO:0000313|EMBL:NXE24583.1};
GN ORFNames=ARDKOR_R03775 {ECO:0000313|EMBL:NXE24583.1};
OS Ardeotis kori.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Otidimorphae; Otidiformes;
OC Otididae; Ardeotis.
OX NCBI_TaxID=89386 {ECO:0000313|EMBL:NXE24583.1, ECO:0000313|Proteomes:UP000560386};
RN [1] {ECO:0000313|EMBL:NXE24583.1, ECO:0000313|Proteomes:UP000560386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-CU-031-01 {ECO:0000313|EMBL:NXE24583.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXE24583.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXE24583.1}.
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DR EMBL; VWPR01000664; NXE24583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8L7Y4; -.
DR Proteomes; UP000560386; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0036122; F:BMP binding; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:TreeGrafter.
DR GO; GO:0048731; P:system development; IEA:UniProtKB-ARBA.
DR FunFam; 2.10.70.10:FF:000005; Chordin-like 1, isoform CRA_c; 1.
DR Gene3D; 6.20.200.20; -; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR045716; CHRDL_1/2_C.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF2; CHORDIN-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19548; CHRDL_1_2_C; 1.
DR Pfam; PF00093; VWC; 1.
DR Pfam; PF23334; VWC2L_2nd; 2.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 3.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000560386};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 36..101
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 115..181
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 262..327
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXE24583.1"
FT NON_TER 456
FT /evidence="ECO:0000313|EMBL:NXE24583.1"
SQ SEQUENCE 456 AA; 52219 MW; 0F6286953FE07101 CRC64;
MRKKWILEDF HFISFGVLCL LFIDGGKLEQ VKHSDTYCVF QDKKYRVGER WHPYLEPYGL
VYCVNCLCSE NGNVLCSRIR CPSLHCPSPV HVPQLCCPRC PEDSLFSVSS KITGKSCEYN
GTTYHHGEMF VAEGLFQNRQ ANQCAQCSCS EGNVYCGLKT CPKLTCSFPV SVPESCCPVC
RGDGELSWEH SDGDIFRQPA NREARHSYHR SHYDLSPSSA RQVVNIPRFP NARSNRGVLP
DPQQASGTIV QIVINNKHKH GRVCVSNGKT YSHGESWHPN LRAFGIVECV LCTCNITKQE
CKKIHCPEQY PCKYPQKVEG KCCKVCPEEV PSQTFDNKDY FCGKETFPVY ESIFTEEGET
IRKIAVETEK PPQVEIHVWT IRKGILRHFY VEKVSKREFE ELPYFKQITR TTPSQWKIFS
EGEAQISQMC ESRVCRTELE DLVKVLYLEK SEKGHC
//
