ID A0A7K8P1I7_COCCO Unreviewed; 148 AA.
AC A0A7K8P1I7;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=Centrosomal protein 20 {ECO:0000256|ARBA:ARBA00070736};
DE AltName: Full=FGFR1OP N-terminal-like protein {ECO:0000256|ARBA:ARBA00076755};
DE AltName: Full=LisH domain-containing protein FOPNL {ECO:0000256|ARBA:ARBA00081996};
DE Flags: Fragment;
GN Name=Fopnl {ECO:0000313|EMBL:NXE73167.1};
GN ORFNames=COCCOC_R00089 {ECO:0000313|EMBL:NXE73167.1};
OS Cochlearius cochlearius (Boat-billed heron).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes;
OC Ardeidae; Cochlearius.
OX NCBI_TaxID=110676 {ECO:0000313|EMBL:NXE73167.1, ECO:0000313|Proteomes:UP000525205};
RN [1] {ECO:0000313|EMBL:NXE73167.1, ECO:0000313|Proteomes:UP000525205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-CU-031-03 {ECO:0000313|EMBL:NXE73167.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXE73167.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the biogenesis of cilia. Required for the
CC recruitment of PLK1 to centrosomes and S phase progression.
CC {ECO:0000256|ARBA:ARBA00055043}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}. Cytoplasmic granule
CC {ECO:0000256|ARBA:ARBA00004463}.
CC -!- SIMILARITY: Belongs to the CEP43 family.
CC {ECO:0000256|ARBA:ARBA00005385}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXE73167.1}.
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DR EMBL; VWPP01000021; NXE73167.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8P1I7; -.
DR Proteomes; UP000525205; Unassembled WGS sequence.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:UniProtKB-ARBA.
DR GO; GO:0031514; C:motile cilium; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR FunFam; 1.20.960.40:FF:000002; LisH domain-containing protein FOPNL; 1.
DR Gene3D; 1.20.960.40; -; 1.
DR InterPro; IPR018993; FOP_dimerisation-dom_N.
DR InterPro; IPR006594; LisH.
DR PANTHER; PTHR15431:SF19; CENTROSOMAL PROTEIN 20-RELATED; 1.
DR PANTHER; PTHR15431; FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF09398; FOP_dimer; 1.
DR PROSITE; PS50896; LISH; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000525205}.
FT DOMAIN 41..111
FT /note="FGFR1 oncogene partner (FOP) N-terminal
FT dimerisation"
FT /evidence="ECO:0000259|Pfam:PF09398"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXE73167.1"
FT NON_TER 148
FT /evidence="ECO:0000313|EMBL:NXE73167.1"
SQ SEQUENCE 148 AA; 16759 MW; 99A9A90357207DF3 CRC64;
QIFFMVIVLK DTLEKRGALG QIKARIRAEV FNALDDQSEP RPPLSHENLL INELIREYLE
YNKYKYAASV LTAESGQPEV PLDRQFLAKE LNIVEDASGK SVPLLYGIIS HFLHGGKEES
IQNTLAKVSL LNYPKQNLGK PPTERNKK
//
