ID A0A7K8QH81_9PASS Unreviewed; 936 AA.
AC A0A7K8QH81;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 16.
DE RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000256|ARBA:ARBA00069395};
DE Flags: Fragment;
GN Name=Sart3 {ECO:0000313|EMBL:NXF04122.1};
GN ORFNames=SMICAP_R02931 {ECO:0000313|EMBL:NXF04122.1};
OS Smithornis capensis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Eurylaimidae; Smithornis.
OX NCBI_TaxID=363769 {ECO:0000313|EMBL:NXF04122.1, ECO:0000313|Proteomes:UP000567624};
RN [1] {ECO:0000313|EMBL:NXF04122.1, ECO:0000313|Proteomes:UP000567624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-CU-031-20 {ECO:0000313|EMBL:NXF04122.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}. Nucleus, Cajal body
CC {ECO:0000256|ARBA:ARBA00004408}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXF04122.1}.
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DR EMBL; VWYW01000062; NXF04122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K8QH81; -.
DR Proteomes; UP000567624; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd12391; RRM1_SART3; 1.
DR CDD; cd12392; RRM2_SART3; 1.
DR FunFam; 1.25.40.10:FF:000081; squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 1.25.40.10:FF:000098; Squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 3.30.70.330:FF:000229; Squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 3.30.70.330:FF:000271; squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034217; SART3_RRM1.
DR InterPro; IPR034218; SART3_RRM2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR17204; PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; 1.
DR PANTHER; PTHR17204:SF25; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF23241; HAT_PRP39_C; 1.
DR Pfam; PF23240; HAT_PRP39_N; 1.
DR Pfam; PF16605; LSM_int_assoc; 1.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00386; HAT; 7.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000567624};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 680..758
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 777..854
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..11
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..57
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..619
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..915
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXF04122.1"
FT NON_TER 936
FT /evidence="ECO:0000313|EMBL:NXF04122.1"
SQ SEQUENCE 936 AA; 106818 MW; 0FFD5A4009108442 CRC64;
ERGGRRTELH KMAAAGAEAA AEEEKRLPEG DPESGGDSDD EGDSDSSGDG EDEEKENEAE
IQRLEEQLSI NAFDYNCHLD LIKLLRQEGE LVKLRRARQK MSELFPLTEE IWLDWLKDEI
KMASENSERE KVYELFERAV KDYICPEIWL EYAQYSIGGI GQEGGIEKVR SIFERALTAV
GLHVTRGTAL WEAYREFENA ILETAQPAPG SVPSPEQQQM LCSQLEKIHT LFRRQLGIPL
LDMEASYAEY EEWSEEPIPE TTVKNYKKAL QQLEKCKPYE EALLSAETPK LAEYQAYIDF
EMKAGDPARI QLIYERALAE NCLVPDLWAR YNRYLDRQLK VKELVLSAHD RAVRNCPWTV
GLWVRYLLAM ERHRVDHSSI SEIFEKALNA GFIQATDYVE IWQAYLDYLR RRVDFTQDSS
KELEELRSAF ARAVEYLKQE VEERFSESGD PSCTIMQNWA RVEARLCNNM QKARELWDNI
MTKGNAKYAN MWLEYYNLER AHGDTQHCRK ALHRAMQCTS DYPEHVCEVL LTLERIEGTL
EDWDAAVQKT ENRLARVNEQ RAKAAEKEAA LAKQEEEKAE QRKQARAEKK ASKKARKTRI
GEKRKANDED EGEWGQEEEQ PSKRHRGEGD GVLPEEDMEV EAGLFGRSAP ADGPAHPKEK
ASTSRKDIPK VLHDSSKDKV TVFVSNLSYN MAEPEVKLRE LFGSCGEVAE IRPVFSNRGT
FRGYCYVQFQ EEGSALQALR LDRTAVEGRP MFVSPCVDKN KNPDFKVFRY STTLEKHKLF
ISGLPFSCTK EELEDVCKAH GNVKDIRLVT NRAGKPKGLA YVEYENEAQA SQAVLKMDGL
TMKDHVIKVM ISNPPLRRLP EAGRASPFPA PRQAYGARGK GRTQLSMMPR ALQRQSNPVA
KAENGVVQNS PATSSEPPEE PKKMSNADFA KMLLKK
//
