ID A0A7K9CYE8_9AVES Unreviewed; 326 AA.
AC A0A7K9CYE8;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
DE Flags: Fragment;
GN Name=Bbs5 {ECO:0000313|EMBL:NXG56345.1};
GN ORFNames=HEMCOM_R05774 {ECO:0000313|EMBL:NXG56345.1};
OS Hemiprocne comata.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Strisores; Apodiformes; Apodidae;
OC Hemiprocninae; Hemiprocne.
OX NCBI_TaxID=243314 {ECO:0000313|EMBL:NXG56345.1, ECO:0000313|Proteomes:UP000518305};
RN [1] {ECO:0000313|EMBL:NXG56345.1, ECO:0000313|Proteomes:UP000518305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-23 {ECO:0000313|EMBL:NXG56345.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXG56345.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXG56345.1}.
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DR EMBL; VWZJ01002168; NXG56345.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K9CYE8; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000518305; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR CDD; cd00900; PH-like; 1.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000518305}.
FT DOMAIN 14..68
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 144..198
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXG56345.1"
FT NON_TER 326
FT /evidence="ECO:0000313|EMBL:NXG56345.1"
SQ SEQUENCE 326 AA; 37375 MW; 9EB080D58D38CF17 CRC64;
FLLSFRQMKM RPGEVLIDCL ESVEDTKGNN GDRGRLLVTN LRIIWRSLSL PRVNLSVGYN
CIINITTRTA NSKLRGQTEA LYILTKCNNT RFEFIFTNVV PGSPRLFTSV IAVHRAYETS
KMYRDLKLRS ALIQNKQLRL LPQEQIYSKI NGIWNLSSDQ GNLGTFFITN VRIVWHANMN
DSFNVSIPYL QIRSIKIRDS KFGLALVIES SQQSGGYVLG FKIEPVEKLQ EAVKEINSLH
RVYSANPIFG VDYEMEEKPQ PLEDLTVEQV QDDVEIESEH TDAFVAYFAD ENKQHDREPI
FSEELGLAIE KLKDGFTLQG LWEVMT
//
