ID A0A7K9NK43_9CORV Unreviewed; 954 AA.
AC A0A7K9NK43;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 10-JUN-2026, entry version 16.
DE SubName: Full=SYDE2 protein {ECO:0000313|EMBL:NXH87198.1};
DE Flags: Fragment;
GN Name=Syde2 {ECO:0000313|EMBL:NXH87198.1};
GN ORFNames=EDOCOE_R10768 {ECO:0000313|EMBL:NXH87198.1};
OS Edolisoma coerulescens.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Corvoidea; Campephagidae; Edolisoma.
OX NCBI_TaxID=2585810 {ECO:0000313|EMBL:NXH87198.1, ECO:0000313|Proteomes:UP000526889};
RN [1] {ECO:0000313|EMBL:NXH87198.1, ECO:0000313|Proteomes:UP000526889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-25 {ECO:0000313|EMBL:NXH87198.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXH87198.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXH87198.1}.
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DR EMBL; VWZW01004607; NXH87198.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K9NK43; -.
DR Proteomes; UP000526889; Unassembled WGS sequence.
DR GO; GO:0097060; C:synaptic membrane; IEA:TreeGrafter.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR GO; GO:0046578; P:regulation of Ras protein signal transduction; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR FunFam; 1.10.555.10:FF:000031; rho GTPase-activating protein 100F isoform X6; 1.
DR FunFam; 2.60.40.150:FF:000195; Synapse defective Rho GTPase homolog 2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR052118; Rho-GAP_regulator.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR057459; SYDE1/2_C2.
DR PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR PANTHER; PTHR46150:SF1; RHO GTPASE-ACTIVATING PROTEIN SYDE2; 1.
DR Pfam; PF25336; C2_SYDE; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW ProRule:PRU00172}; Reference proteome {ECO:0000313|Proteomes:UP000526889}.
FT DOMAIN 419..538
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 575..790
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..51
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..84
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..127
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..293
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..884
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXH87198.1"
FT NON_TER 954
FT /evidence="ECO:0000313|EMBL:NXH87198.1"
SQ SEQUENCE 954 AA; 105044 MW; C18D748A14EE8E85 CRC64;
DFIENVYIAS RSRKEPKCPQ ASEVPEHRPQ ANSITVSKKR SWLQQSTHRR PPPPLEEEDA
CKEVHGAVIP VPRSPIPLPE PAVPWAPSTS AAGRERPAQS GALQSPAALR STALDCGEDG
DADDEGEIWY NPIPEDDEPD LPGVHPSAVN SLVAVGSPSV RYKAHPGGDS GVATSPHECP
TRSMESTGSS WTAQPGEGSQ ADAAQSGEHA QQHRQKFACK APSVPAAEDN PAFKCPSTGK
WFGAALAHKP DIPSTEVSPP SPSPLKKSGS INWPFPDRIK SPRTVRKLSM KMKKLPELSR
KLSVKGTSSH SSSDNAPSLL KGSCRDTSHT VSLPSSGNST TAASRNVISR YHLDSSVSSQ
HTYKKKSSRS SKSFNKGGYL SDGDSPELIT KSGKHRHETK CGKGKESLPS NSGKPEIDID
AFRHYNFSDQ PKCSQYISGL MSIHFYGAED LKPPRIDSKD VFCAIQVDSV NKARTALLTC
RTTFLDMDHT FNIEIENAQH LKLVVFSWEP TPRKNRVCCH GTVALPTLFR VTKTHQLAVK
LEPRGLIYVK LSLMEQWENS LDGLDTDREP VMFGVDARKV VEKENAGLMV PLLLQKCILE
IEKRGCQVVG LYRLCGSAAV KKELREAFER DSKAVTLCES QYPDINVITG VLKDYLRELP
SPLITKQLYE AVLDAMVKNP LKMTANGCEN DPSDSEHTAA LLDCLPDVEK ATLKMLLDHL
KLVASYHEVN KMTCQNLAVC FGPVLLSQRQ ETTNHNNRVF TDSEELASAL DFKKHIEVLH
YLLQLWPVHH SPPKEPAHLN AFPEHSSSLN YLRPKRQRPQ MLNLSGTEVS GVLRPRPAGL
DSPSSNRYAG DWSSCGENYF LNPRDCLGEA DYDDIPSEDT ESGDESSKAE ELDVPARRPQ
PSPGEHAFGS YLTVQAMDSA VDHRANLKDL QESIDTLIGN LERELNKNKL NMSY
//
