ID A0A7K9VN26_ANSSE Unreviewed; 733 AA.
AC A0A7K9VN26;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 10-JUN-2026, entry version 16.
DE SubName: Full=GLIS1 protein {ECO:0000313|EMBL:NXI74124.1};
DE Flags: Fragment;
GN Name=Glis1 {ECO:0000313|EMBL:NXI74124.1};
GN ORFNames=ANSSEM_R06054 {ECO:0000313|EMBL:NXI74124.1};
OS Anseranas semipalmata (Magpie goose) (Anas semipalmata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anseranatidae;
OC Anseranas.
OX NCBI_TaxID=8851 {ECO:0000313|EMBL:NXI74124.1, ECO:0000313|Proteomes:UP000567872};
RN [1] {ECO:0000313|EMBL:NXI74124.1, ECO:0000313|Proteomes:UP000567872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-57 {ECO:0000313|EMBL:NXI74124.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXI74124.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the GLI C2H2-type zinc-finger protein family.
CC {ECO:0000256|ARBA:ARBA00010831}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXI74124.1}.
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DR EMBL; VXAA01007048; NXI74124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K9VN26; -.
DR OrthoDB; 3214149at2759; -.
DR Proteomes; UP000567872; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-KW.
DR FunFam; 3.30.160.60:FF:000019; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000031; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000036; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000048; GLI family zinc finger 3; 1.
DR FunFam; 3.30.160.60:FF:000453; GLIS family zinc finger 3; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR043359; GLI-like.
DR InterPro; IPR048420; Zap1-like_Znf1.
DR InterPro; IPR056436; Znf-C2H2_ZIC1-5/GLI1-3-like.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45718; TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS; 1.
DR PANTHER; PTHR45718:SF3; ZINC FINGER PROTEIN GLIS1; 1.
DR Pfam; PF21816; Zap1_zf1; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF23561; zf-C2H2_15; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000567872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 315..345
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 349..381
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 382..411
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 412..441
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 442..471
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 212..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXI74124.1"
FT NON_TER 733
FT /evidence="ECO:0000313|EMBL:NXI74124.1"
SQ SEQUENCE 733 AA; 80951 MW; 7B735D85C49BD151 CRC64;
NGGYNHCNLI SEKKNMMDME MTSSSVPVCR QGLFIHTGNP LMRDHPLSCE RLLHVGQLNL
THSDIRFQDS VDSAAPCLNG SHPAQHIKQE CPSDYKVLSE ASTHRRITEG MELRASGSLH
PEIDLMNNSF TNSLSSYLFN NEHSSSLGPL SLGTPQHSAR LQTSNLKKRC ISVVPSSAEG
IDITAIIRTS QTSLVTCVNG LRTNSAGISS HPVEISHHSA QKSSRPQSCS QPGNPCSIPS
PPACLKVSFL KQEPADDYSS TADLFRHHQG LPPPYHLHQQ LSQTQGTLPH LHASMSPKSL
QPSEGDEQDL GNGKQVCRWI DCSATYDQQD ELVRHIEKTH IDQRKGEDFT CFWAGCVRRY
KPFNARYKLL IHMRVHSGEK PNKCMFEGCN KAFSRLENLK IHLRSHTGEK PYLCQHPGCQ
KAFSNSSDRA KHQRTHLDTK PYACQIPGCS KRYTDPSSLR KHVKAHSAKE QQVRKKLNSC
TDIEQDVLSE CLAIQQLHTS SQHILDGKCG RSVGHHDLIT GMYSGSSANH NGPSPGLLPP
PHDIPSRHHP LDSTLSSPHH HQSPLESARE GLAPNIISPL VSPLKALVPP SLLQKHGSPS
SHSQSPNGQQ FSGIPNKPYA QFQNQSVQQG SQGYQGSFHS IQNCFHYGDC YRTMDQSVTS
DVLTGESHCF NPLRQNGYHI LNAPLASTGY DAISEAQCVS EDMVSNGTDE NGFFQNGAFD
HCLNHIPPIY TDT
//
