ID A0A7K9Z240_9GALL Unreviewed; 455 AA.
AC A0A7K9Z240;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 02-APR-2025, entry version 15.
DE SubName: Full=TFEB factor {ECO:0000313|EMBL:NXJ15324.1};
DE Flags: Fragment;
GN Name=Tfeb {ECO:0000313|EMBL:NXJ15324.1};
GN ORFNames=ODOGUJ_R08578 {ECO:0000313|EMBL:NXJ15324.1};
OS Odontophorus gujanensis (marbled wood quail).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Odontophoridae;
OC Odontophorus.
OX NCBI_TaxID=886794 {ECO:0000313|EMBL:NXJ15324.1, ECO:0000313|Proteomes:UP000522663};
RN [1] {ECO:0000313|EMBL:NXJ15324.1, ECO:0000313|Proteomes:UP000522663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-53 {ECO:0000313|EMBL:NXJ15324.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXJ15324.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MiT/TFE family.
CC {ECO:0000256|ARBA:ARBA00008289}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXJ15324.1}.
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DR EMBL; VXAB01012871; NXJ15324.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K9Z240; -.
DR OrthoDB; 6242697at2759; -.
DR Proteomes; UP000522663; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006959; P:humoral immune response; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18927; bHLHzip_TFEB; 1.
DR FunFam; 4.10.280.10:FF:000003; microphthalmia-associated transcription factor isoform X1; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR024098; bHLHzip_TFEB.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR021802; MiT/TFE_C.
DR InterPro; IPR031867; MiT/TFE_N.
DR PANTHER; PTHR45776; MIP04163P; 1.
DR PANTHER; PTHR45776:SF5; TRANSCRIPTION FACTOR EB; 1.
DR Pfam; PF11851; DUF3371; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF15951; MITF_TFEB_C_3_N; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000522663};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 229..282
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 101..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..138
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..372
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..405
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..448
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXJ15324.1"
FT NON_TER 455
FT /evidence="ECO:0000313|EMBL:NXJ15324.1"
SQ SEQUENCE 455 AA; 50823 MW; 356B28CD0D66B4DD CRC64;
MASRIGLRME LMKQQAQQEA ERERAQQQLM MNYMQQQRMP VASTPAINTP VHYQSPPPVP
GEVLKVQSYL ENPTTYHLQK SRDKKVQAYL SETYGNKFAA HVSPASHSPK PPPAVSPSVR
PGHVMSSSAG NSAPNSPMAM LNIGSNPERE FDEVIDDIMR LDDVLGYMNP EVHMPNTLPM
SSSHMNVYSG DPQVTASLVG VTSSSCPAEL TQKRELTDAE SRALAKERQK KDNHNLIERR
RRFNINDRIK ELGMLIPKAN DLDVRWNKGT ILKASVDYIK RMQKDLQRSR DLENHSRRLE
MTNKQLLLRI QELEMQARVH GLPTSSPSGV NVAELAQQVV KQEAGTDEGM LEPLLPTPDP
ESQPVLPPPP QSPYHQLDFT HSLSFDDGSQ GFPDNLEPSH SSSFPSLSKK ELDLMLLQDT
MLPLASDPLF SAVSPEASKA SSRRSSFSME DTDML
//
