ID A0A7L0BZJ6_9AVES Unreviewed; 154 AA.
AC A0A7L0BZJ6;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE SubName: Full=FOXA2 factor {ECO:0000313|EMBL:NXJ52687.1};
DE Flags: Fragment;
GN Name=Foxa2 {ECO:0000313|EMBL:NXJ52687.1};
GN ORFNames=SPITYR_R08438 {ECO:0000313|EMBL:NXJ52687.1};
OS Spizaetus tyrannus (black hawk-eagle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae;
OC Accipitriformes; Accipitridae; Accipitrinae; Spizaetus.
OX NCBI_TaxID=252798 {ECO:0000313|EMBL:NXJ52687.1, ECO:0000313|Proteomes:UP000519115};
RN [1] {ECO:0000313|EMBL:NXJ52687.1, ECO:0000313|Proteomes:UP000519115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-007-42 {ECO:0000313|EMBL:NXJ52687.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXJ52687.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXJ52687.1}.
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DR EMBL; VXAF01000463; NXJ52687.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0BZJ6; -.
DR Proteomes; UP000519115; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR CDD; cd20039; FH_FOXA2; 1.
DR FunFam; 1.10.10.10:FF:000042; hepatocyte nuclear factor 3-beta; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF167; HEPATOCYTE NUCLEAR FACTOR 3-BETA; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000519115}.
FT DOMAIN 1..95
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 1..95
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 101..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..122
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..154
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXJ52687.1"
FT NON_TER 154
FT /evidence="ECO:0000313|EMBL:NXJ52687.1"
SQ SEQUENCE 154 AA; 16661 MW; 8977A53F89050535 CRC64;
KPPYSYISLI TMAIQQSPNK MLTLSEIYQW IMDLFPFYRQ NQQRWQNSIR HSLSFNDCFL
KVPRSPDKPG KGSFWTLHPD SGNMFENGCY LRRQKRFKCE KQLAAKDSGG AGSGAGGGGK
KGPGQPPSQP LGEGSSSGGS EGSAGAESPA SASP
//
