ID A0A7L0C0U5_9AVES Unreviewed; 327 AA.
AC A0A7L0C0U5;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
DE Flags: Fragment;
GN Name=Bbs5 {ECO:0000313|EMBL:NXJ52516.1};
GN ORFNames=SPITYR_R08062 {ECO:0000313|EMBL:NXJ52516.1};
OS Spizaetus tyrannus (black hawk-eagle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae;
OC Accipitriformes; Accipitridae; Accipitrinae; Spizaetus.
OX NCBI_TaxID=252798 {ECO:0000313|EMBL:NXJ52516.1, ECO:0000313|Proteomes:UP000519115};
RN [1] {ECO:0000313|EMBL:NXJ52516.1, ECO:0000313|Proteomes:UP000519115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-007-42 {ECO:0000313|EMBL:NXJ52516.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXJ52516.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXJ52516.1}.
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DR EMBL; VXAF01000446; NXJ52516.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0C0U5; -.
DR Proteomes; UP000519115; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR CDD; cd00900; PH-like; 1.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000519115}.
FT DOMAIN 14..68
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 144..198
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXJ52516.1"
FT NON_TER 327
FT /evidence="ECO:0000313|EMBL:NXJ52516.1"
SQ SEQUENCE 327 AA; 37544 MW; A737B318F1D9579D CRC64;
FFFSFRQMKM RPGEVLIDCL ESVEDTKGNN GDRGRLLVTN LRIIWRSLSL PRVNLSVGYN
CIINITTRTA NSKLRGQTEA LYILTKCNNT RFEFIFTNVV PGSPRLFTSV IAVHRAYETS
KMYRDLKLRS ALIQNKQLRL LPQEQIYDKI NGVWNLSSDQ GNLGTFFITN VRIVWHANMN
DSFNVSIPYL QIRSIKIRDS KFGLALVIES SQQSGGYVLG FKIDPVEKLQ EAVKEINSLH
RVYSANPIFG VDYEMEEKPQ PLEDLTVEQV QDDVEIESDE HTDAFVAYFA DENKQHDREP
VFSEELGLAI EKLKDGFTLQ GLWEVMT
//
