ID A0A7L0I1F5_AREIN Unreviewed; 908 AA.
AC A0A7L0I1F5;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE SubName: Full=MEG11 protein {ECO:0000313|EMBL:NXK25618.1};
DE Flags: Fragment;
GN Name=Megf11 {ECO:0000313|EMBL:NXK25618.1};
GN ORFNames=AREINT_R11078 {ECO:0000313|EMBL:NXK25618.1};
OS Arenaria interpres (Ruddy turnstone) (Tringa interpres).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Scolopacidae;
OC Arenaria.
OX NCBI_TaxID=54971 {ECO:0000313|EMBL:NXK25618.1, ECO:0000313|Proteomes:UP000541811};
RN [1] {ECO:0000313|EMBL:NXK25618.1, ECO:0000313|Proteomes:UP000541811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-005-73 {ECO:0000313|EMBL:NXK25618.1};
RC TISSUE=Liver {ECO:0000313|EMBL:NXK25618.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
CC -!- SIMILARITY: Belongs to the MEGF family.
CC {ECO:0000256|ARBA:ARBA00038377}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXK25618.1}.
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DR EMBL; VXAK01020144; NXK25618.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0I1F5; -.
DR Proteomes; UP000541811; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR FunFam; 2.170.300.10:FF:000007; multiple epidermal growth factor-like domains protein 10; 1.
DR FunFam; 2.10.25.10:FF:000114; Multiple epidermal growth factor-like domains protein 11; 1.
DR FunFam; 2.170.300.10:FF:000005; multiple epidermal growth factor-like domains protein 11; 1.
DR FunFam; 2.170.300.10:FF:000006; Multiple epidermal growth factor-like domains protein 11; 1.
DR FunFam; 2.170.300.10:FF:000021; Platelet endothelial aggregation receptor 1; 1.
DR FunFam; 2.170.300.10:FF:000041; Tyrosine protein kinase receptor tie-1, putative; 2.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 6.
DR InterPro; IPR000742; EGF.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR057138; EGF_PEAR1L-like.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR052485; MEGF_diff_regulators.
DR PANTHER; PTHR24052; DELTA-RELATED; 1.
DR PANTHER; PTHR24052:SF13; MULTIPLE EGF LIKE DOMAINS 11; 1.
DR Pfam; PF00053; EGF_laminin; 8.
DR Pfam; PF23301; EGF_PEAR1L; 1.
DR Pfam; PF23106; EGF_Teneurin; 1.
DR Pfam; PF12661; hEGF; 2.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 17.
DR SMART; SM00180; EGF_Lam; 16.
DR PROSITE; PS00022; EGF_1; 15.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 10.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51041; EMI; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000541811};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..908
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029817736"
FT TRANSMEM 854..877
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..106
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 148..178
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 186..221
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 229..264
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 272..307
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 315..350
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 404..439
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 490..525
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 576..611
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 707..742
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 755..785
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 758..799
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 168..177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 211..220
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 254..263
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 297..306
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 340..349
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 429..438
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 515..524
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 601..610
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 732..741
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 775..784
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXK25618.1"
FT NON_TER 908
FT /evidence="ECO:0000313|EMBL:NXK25618.1"
SQ SEQUENCE 908 AA; 97989 MW; 25328C5C9F6AB978 CRC64;
VAHMLFKWIL KGLTLSFLLQ TTLSLNPDDP NVCSHWESYA VTVQESYAHP FDQIYYTRCT
DILNWFKCTR HRISYKTAYR RGLRTMYRRR SQCCPGYYES GDYCIPLCTE ECVHGRCVSP
DTCHCEPGWG GTDCSSGCDS EHWGPHCSNR CQCQNEALCN PITGACVCAD GYQGWRCEEL
CDPGTYGKGC QFPCQCHNGA TCDHRTGECH CAPGYTGVFC EELCPPGSHG AQCELRCPCQ
NGGVCHHITG ECSCPAGWTG LVCAQPCPPG TFGINCSQDC PCHNGGHCDP VTGKCICTAG
YIGDRCQEEC PIGTYGFQCT QRCDCQNGAK CYHVNGACMC DPGFKGIHCQ ERMCPEGLYG
LKCNKRCPCN VTNTLSCHPL SGECSCKAGW AGLYCNETCP PGYYGEGCQL TCPCQNGADC
DSITGKCLCA PGYMGDDCSF TCMAGTYGTN CSSVCNCKND GACSPVDGLC YCKEGWQGVD
CSIPCSSGSW GLNCNQTCYC TNGAACRPAD GFCLCSPGWQ GDYCDQPCPD GTYGLNCSER
CDCNHADGCD PVTGYCCCLA GWTGIHCDNI CTQGRWGPNC SISCNCENGG SCSPEDGTCD
CAPGYRGPLC QRICPPGFYG HHCSQPCPQC VHSSGPCHHV SGHCDCLPGF FGALCNQVCP
SGKYGKNCAE VCQCTENGTC NPIDGSCQCF PGWIGTDCSQ TCPTGFWGPD CFHSCNCHNG
ALCSPYDGEC RCTHGWTGLY CTQRCPAAFY GKNCANVCQC QNGADCDHIT GQCTCRTGFT
GKQCEQKCSP GTFGYGCKQL CECMNNATCD HVTGTCYCSP GFKGIRCDQA ALMMEELNPY
TKISPALGSE RHSVGAIIGI IILLLIIMVL LALFVWYRRK QKEKGHDMPS VSYTPAMRMT
NTDYSLSG
//
