ID A0A7L0LM36_9SYLV Unreviewed; 970 AA.
AC A0A7L0LM36;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 16.
DE SubName: Full=SMCA5 regulator {ECO:0000313|EMBL:NXK70246.1};
DE Flags: Fragment;
GN Name=Smarca5 {ECO:0000313|EMBL:NXK70246.1};
GN ORFNames=SYLVIR_R01270 {ECO:0000313|EMBL:NXK70246.1};
OS Sylvietta virens (Green crombec).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Sylviidae; Acrocephalinae; Sylvietta.
OX NCBI_TaxID=208069 {ECO:0000313|EMBL:NXK70246.1, ECO:0000313|Proteomes:UP000567822};
RN [1] {ECO:0000313|EMBL:NXK70246.1, ECO:0000313|Proteomes:UP000567822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-009-59 {ECO:0000313|EMBL:NXK70246.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXK70246.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
CC {ECO:0000256|ARBA:ARBA00009687}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXK70246.1}.
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DR EMBL; VXAN01000982; NXK70246.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0LM36; -.
DR Proteomes; UP000567822; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:TreeGrafter.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:TreeGrafter.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:TreeGrafter.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0042393; F:histone binding; IEA:TreeGrafter.
DR GO; GO:0031491; F:nucleosome binding; IEA:InterPro.
DR GO; GO:0034728; P:nucleosome organization; IEA:TreeGrafter.
DR CDD; cd18064; DEXHc_SMARCA5; 1.
DR CDD; cd00167; SANT; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR FunFam; 3.40.50.300:FF:000082; ISWI chromatin remodeling complex ATPase ISW1; 1.
DR FunFam; 1.10.10.60:FF:000022; ISWI chromatin-remodeling complex ATPase CHR11 isoform A; 1.
DR FunFam; 1.10.10.60:FF:000049; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member; 1.
DR FunFam; 1.10.1040.30:FF:000001; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member; 1.
DR FunFam; 1.20.5.1190:FF:000002; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member; 1.
DR FunFam; 3.40.50.10810:FF:000101; SWI/SNF-related, matrix-associated, actin-dependent regulator of; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.20.5.1190; iswi atpase; 1.
DR Gene3D; 1.10.1040.30; ISWI, HAND domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR015194; ISWI_HAND-dom.
DR InterPro; IPR036306; ISWI_HAND-dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR PANTHER; PTHR45623:SF54; SWI_SNF RELATED, MATRIX ASSOCIATED, ACTIN DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 5; 1.
DR Pfam; PF09110; HAND; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF101224; HAND domain of the nucleosome remodeling ATPase ISWI; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000567822};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 109..274
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 404..555
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 757..809
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 27..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXK70246.1"
FT NON_TER 970
FT /evidence="ECO:0000313|EMBL:NXK70246.1"
SQ SEQUENCE 970 AA; 113792 MW; 0DCE3CE4F2090946 CRC64;
QQTDRANRFE YLLKQTELFA HFIQPAAQKT PTSPLKMKPG RPRIKKDEKQ NLLSAGDYRH
RRTEQEEDEE LLTESSKTTN VCTRFEESPS YVKWGKLRDY QIRGLNWLIS LYENGINGIL
ADEMGLGKTL QTISLLGYMK HYRNIPGPHM VLVPKSTLQN WMNEFKRWVP TLRAVCLIGD
KDQRAAFVRD VLLPGEWDVC VTSYEMLIKE KSVFKKFNWR YLVIDEAHRI KNEKSKLSEI
VREFKTTNRL LLTGTPLQNN LHELWALLNF LLPDVFNSAE DFDSWFDTNN CLGDQKLVER
LHMVLRPFLL RRIKADVEKS LPPKKEVKIY VGLSKMQREW YTRILMKDID ILNSAGKLDK
MRLLNILMQL RKCCNHPYLF DGAEPGPPYT TDMHLVTNSG KMVVLDKLLP KLKEQGSRVL
IFSQMTRVLD ILEDYCMWRN YEYCRLDGQT PHNERQASIN AFNDPDSSKF VFMLSTRAGG
LGINLATADV VILYDSDWNP QVDLQAMDRA HRIGQTKTVR VFRFITDNTV EERIVERAEM
KLRLDSIVIQ QGKLVDQNLN KLGKDEMLQM IRHGATHVFA SKDSEITDED IDHILERGAK
KTAEMNEKLS KMGESSLRNF TMDTESSVYN FEGEDYREKQ KLAFTEWIEP PKRERKANYA
VDAYFREALR VSEPKAPKAP RPPKQPNVQD FQFFPPRLFE LLEKEILYYR KTIGYKVPRN
PDLPNAAQAQ KEEQLKIDEA EPLNDEELEE KEKLLTQGFT NWNKRDFNQF IKANEKWGRD
DIENIAREVE GKTPEEVIEY SAVFWERCNE LQDIEKIMAQ IERGEARIQR RISIKKALDT
KIGRYKAPFH QLRISYGTNK GKNYTEEEDR FLICMLHKLG FDKENVYDEL RQCIRNSPQF
RFDWFLKSRT AMELQRRCNT LITLIERENM ELEEKEKAEK KKRGPKPSSA QKRKMDGTPD
GRGRKKKLKL
//
