ID A0A7L0P9Q0_9AVES Unreviewed; 1202 AA.
AC A0A7L0P9Q0;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE SubName: Full=AFF1 protein {ECO:0000313|EMBL:NXL02647.1};
DE Flags: Fragment;
GN Name=Aff1 {ECO:0000313|EMBL:NXL02647.1};
GN ORFNames=MESCAY_R06679 {ECO:0000313|EMBL:NXL02647.1};
OS Mesembrinibis cayennensis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes;
OC Threskiornithidae; Mesembrinibis.
OX NCBI_TaxID=1118748 {ECO:0000313|EMBL:NXL02647.1, ECO:0000313|Proteomes:UP000574277};
RN [1] {ECO:0000313|EMBL:NXL02647.1, ECO:0000313|Proteomes:UP000574277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-44 {ECO:0000313|EMBL:NXL02647.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXL02647.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXL02647.1}.
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DR EMBL; VXAT01005714; NXL02647.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0P9Q0; -.
DR Proteomes; UP000574277; Unassembled WGS sequence.
DR GO; GO:0032783; C:super elongation complex; IEA:TreeGrafter.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 6.10.250.2670; -; 1.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR InterPro; IPR043639; AF4_int.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF6; AF4_FMR2 FAMILY MEMBER 1; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18875; AF4_int; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000574277}.
FT DOMAIN 937..1201
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1077..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..215
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..269
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..453
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..473
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..638
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..736
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..863
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXL02647.1"
FT NON_TER 1202
FT /evidence="ECO:0000313|EMBL:NXL02647.1"
SQ SEQUENCE 1202 AA; 132577 MW; 87A5919C9E3D3B6A CRC64;
NEDRNLLRIR EKERRNQEAL QEKDKFPEKT PLFAEPYKTN KEDELSSRIQ NMLGNYEEVK
EFISNKSHQN LIGIPESVAP LIPQGKPNRP YFPEKTSHTL PSSFHRTTRH PPMGPTVVAR
PPPSHSIHYQ KAQSRTEPAS GLHAKSHSLS NGRSQGQEHN RGGQESHTGF HHKRNDRRAV
GEGRANELQT SLLALSPLLS SLSSPVAPLS PLHSSQHINS RSQNSSKSHG PTYSQTKSSQ
DLATASQEKE SRDSSTVNLT STTQPSSQTF PPPLPSKTSA MQQKPTAYVR PMDGQDQAPV
ESPELKPLLE EYHGEPYEKI SDLKANAKAK LSKLEIPSEP IEQTFPSDVH SIEEILKEMT
HSWPPPLTAI HTPSTAEPSK FPFPTKESQH VGSVAQNQKQ YDAPSKTLPS SQPRTSMLQD
DLQLSDSEES GDDQVVEKPP SSLAPPSALQ SQPKSVASAH SSSPESGSTS DSDSSSDSET
ESNSSDSEAN DPPRASVPEP DPPTSNKWQL DNWLTKVNPP AAPTESLSEI THGDGCEESK
EQGQGISSNS SHQRAEPREP HHKSSSRVAR APQDAHLPTK RNCQKSPVRT EEPSPRQTVG
IKRPGKAPVH EGPKGHLKVE SDPGPFEVRD QSSRDKPKVK TKGKPKSGDR KDLKPALQEP
AENRKHKSSH QANAKPVLDP KLMRDVGSAQ EHLALSPLPQ GQGTTPTRTS GHRPAVMARE
DFHKEKLPLP IREKKLLSPV RDSPAPQSLM VKIDLPLLSR VPQPPGKDSH QKRAEAKELP
SAKKQDLERK TMDTPDKSLQ KRKREVEKEI DRKKKKSEKE TKSLQSSANK DSNKLKASKA
SFESQKKDLL LPPPLPPMSP AHPAPKSTKM AQKRPRNESG ELPAMDNTAR NKSNHKDPLF
AKHKKVERSH AELSKGIKGS AGDDTNPFPV PSLPNGTSKP RRPQLKFDRQ HPVEYYIEEA
KRLKHKADAM TDKIGKAFQY LDAALSFIEY GIALESDAPA PKSAYSIFSD TIDLIKFVMT
LKSFTDPSAS SHEKIFAVLC MRCQSILHMA MFRYKKDTAI KYSRILNDHF KSSSRVTQAP
SPCVARSTGM PSPLSPMPSP AGSVSSQPGS NASNCSGNSI GSSITVPYNI PSITSSYVNI
TSYILYAYDI WEQADALARK NKEFFAELST ATCALALNSS MTELVHYSRQ GLQWLRLETN
TP
//
