ID A0A7L0QV80_SETKR Unreviewed; 695 AA.
AC A0A7L0QV80;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 13.
DE SubName: Full=LEPR protein {ECO:0000313|EMBL:NXL20569.1};
DE Flags: Fragment;
GN Name=Lepr {ECO:0000313|EMBL:NXL20569.1};
GN ORFNames=SETKIR_R02929 {ECO:0000313|EMBL:NXL20569.1};
OS Setophaga kirtlandii (Kirtland's warbler) (Dendroica kirtlandii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Passeroidea; Parulidae; Setophaga.
OX NCBI_TaxID=298831 {ECO:0000313|EMBL:NXL20569.1, ECO:0000313|Proteomes:UP000550059};
RN [1] {ECO:0000313|EMBL:NXL20569.1, ECO:0000313|Proteomes:UP000550059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-45 {ECO:0000313|EMBL:NXL20569.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXL20569.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00008921}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXL20569.1}.
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DR EMBL; VXAS01013294; NXL20569.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0QV80; -.
DR Proteomes; UP000550059; Unassembled WGS sequence.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:TreeGrafter.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR FunFam; 2.60.40.10:FF:000494; Leptin receptor; 1.
DR FunFam; 2.60.40.10:FF:000501; Leptin receptor; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003529; Hematopoietin_rcpt_Gp130_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041182; LEP-R_IGD.
DR PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23037:SF44; LEPTIN RECEPTOR; 1.
DR Pfam; PF18589; ObR_Ig; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS01353; HEMATOPO_REC_L_F2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000550059};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..208
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXL20569.1"
FT NON_TER 695
FT /evidence="ECO:0000313|EMBL:NXL20569.1"
SQ SEQUENCE 695 AA; 77120 MW; 6C2D285C448EA02C CRC64;
LDMDFNISCE TDGYLTKMTC RWSANPTTLL LGSLQLRYHR SQIYCSDFPS PSADSEVKEC
LLQRNHSYEC TFQPIFLLSG YTLWIEFKHS LGTLQSSPVC VIPADVVKPL PPSNVGAEVT
RNTGLLNVSW TQPAFASRDL TFQIRWNPGS REDIPWQLYE VPDPAGSWAV VPVQQPCVQY
VVQVRCRELQ GSGYWSDWST AAQSLVQDIR APLQGPEFWR MVSEDPARKQ RNVTLLWKPL
MQNDSLCSVS RYIIQHQTPG SPPWQEFVDH GTSWTFPWRE PTHTITISAM NSVGISAINS
NLTLSQQMST VDAVQSLSAY LVNSTCVVVV WSLSPQIPEI KSFVIEWRNL NKEEQVKWLR
VPPNLRKYFI YDHFILIEKY QFSLYPVFAG GVGKARATDQ FAQGGFETGN AGSLHVVLPI
VFCTSVLLLG ALLLSHQRMK KLLWEDVPNP KNCSWAQGVN FQQPETLEHL FAKHPEPMSC
EPLLLEAEIV LEDISITKTL GKEEPGDFLG IDSTFPTPQD SECASGQSSS SCQDGEAAVQ
GDLRYATLIS SCPSSEPCPP KSCPGRCLGS CFLGQHPIVL GAFCSAAWEV GSGAVLVPQL
SLLSSQPLEQ ALPGRAQRSL CYLGVPALDT GQRDSLTDGP RGTWQPQSTE QEVLQHIPAT
VKELIQSSLK PKGTVPYVPQ FRVAAAKEKE AAEKK
//
