ID A0A7L0QZ94_SETKR Unreviewed; 328 AA.
AC A0A7L0QZ94;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE SubName: Full=WISP3 protein {ECO:0000313|EMBL:NXL22642.1};
DE Flags: Fragment;
GN Name=Wisp3 {ECO:0000313|EMBL:NXL22642.1};
GN ORFNames=SETKIR_R03828 {ECO:0000313|EMBL:NXL22642.1};
OS Setophaga kirtlandii (Kirtland's warbler) (Dendroica kirtlandii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Passeroidea; Parulidae; Setophaga.
OX NCBI_TaxID=298831 {ECO:0000313|EMBL:NXL22642.1, ECO:0000313|Proteomes:UP000550059};
RN [1] {ECO:0000313|EMBL:NXL22642.1, ECO:0000313|Proteomes:UP000550059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-45 {ECO:0000313|EMBL:NXL22642.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXL22642.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the CCN family. {ECO:0000256|ARBA:ARBA00008125}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXL22642.1}.
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DR EMBL; VXAS01016920; NXL22642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L0QZ94; -.
DR Proteomes; UP000550059; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0008201; F:heparin binding; IEA:TreeGrafter.
DR GO; GO:0005178; F:integrin binding; IEA:TreeGrafter.
DR GO; GO:0007155; P:cell adhesion; IEA:TreeGrafter.
DR GO; GO:0045597; P:positive regulation of cell differentiation; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR FunFam; 2.20.100.10:FF:000065; Cellular communication network factor 6; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR050941; CCN.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR006208; Glyco_hormone_CN.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR017891; Insulin_GF-bd_Cys-rich_CS.
DR InterPro; IPR043973; TSP1_CCN.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR11348:SF3; CELLULAR COMMUNICATION NETWORK FACTOR 6; 1.
DR PANTHER; PTHR11348; CONNECTIVE TISSUE GROWTH FACTOR-RELATED; 1.
DR Pfam; PF00007; Cys_knot; 1.
DR Pfam; PF00219; IGFBP; 1.
DR Pfam; PF19035; TSP1_CCN; 1.
DR SMART; SM00041; CT; 1.
DR SMART; SM00121; IB; 1.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS00222; IGFBP_N_1; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000550059};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 19..91
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
FT DOMAIN 242..316
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXL22642.1"
FT NON_TER 328
FT /evidence="ECO:0000313|EMBL:NXL22642.1"
SQ SEQUENCE 328 AA; 36411 MW; 5C3C789F8B406DBD CRC64;
HSPPEQPGDK PSETGEVQRK EVCRWPCRCP PVPACTPGVS LVKDGCGCCK VCAKQAGEPC
NEADVCDPHK GLYCDYSEDE PRYETGVCAY LVAVGCELNG VYYTNGQTFQ PNRLYKCLCV
SGTIGCTPAF TPRLAGSPCA RVPGRKKPGQ SICGLGQHKQ LQSTNYRLMS AYRSLPLVLK
KKCLIQATPW TPCSRTCGIG ISSRVTNDNR KCEMKKEKRL CFIQPCLTNM LKKIKIPKGK
TCQPTFQLPT AEKLVFSGCS TTQRYKLTFC GVCLDKRCCI PNKSKMITVQ FECPNEGFFR
WKMMWITSCV CQRICSAPGD IFSQLKLL
//
