ID A0A7L1AZS4_GYMTI Unreviewed; 306 AA.
AC A0A7L1AZS4;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 17.
DE RecName: Full=Forkhead box protein L2 {ECO:0000256|ARBA:ARBA00034872};
DE Flags: Fragment;
GN Name=Foxl2 {ECO:0000313|EMBL:NXM46782.1};
GN ORFNames=GYMTIB_R09046 {ECO:0000313|EMBL:NXM46782.1};
OS Gymnorhina tibicen (Australian magpie) (Cracticus tibicen).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Artamidae; Gymnorhina.
OX NCBI_TaxID=9132 {ECO:0000313|EMBL:NXM46782.1, ECO:0000313|Proteomes:UP000579941};
RN [1] {ECO:0000313|EMBL:NXM46782.1, ECO:0000313|Proteomes:UP000579941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-05 {ECO:0000313|EMBL:NXM46782.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXM46782.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXM46782.1}.
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DR EMBL; VXAZ01006886; NXM46782.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L1AZS4; -.
DR Proteomes; UP000579941; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd20028; FH_FOXL2; 1.
DR FunFam; 1.10.10.10:FF:000016; Forkhead box protein I1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047515; FH_FOXL2.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF411; FORKHEAD BOX PROTEIN L2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000579941};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 47..141
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 47..141
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..250
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXM46782.1"
FT NON_TER 306
FT /evidence="ECO:0000313|EMBL:NXM46782.1"
SQ SEQUENCE 306 AA; 34210 MW; 3F234AE85F81D554 CRC64;
MMSNYPDGEE DTVALLAHDT SGSKEPDRGK EELSADKGPE KPDPSQKPPY SYVALIAMAI
RESAEKRLTL SGIYQYIISK FPFYEKNKKG WQNSIRHNLS LNECFIKVPR EGGGERKGNY
WTLDPACEDM FEKGNYRRRR RMKRPFRPPP THFQPGKTLF SPDSYGYLSP PKYLQSTFMN
NSWPLGQPPA PMPYTSCQMS GGNVSPVNVK GLSGPASYNP YSRVQSMALP SMVNSYNGMG
HHHHHPHAHH PQQLSPASPA PPAAPAANGA GLQFACARQP AELSMMHCSY WEHDSKHSAL
HSRIDI
//
