ID A0A7L1EKH8_OENON Unreviewed; 249 AA.
AC A0A7L1EKH8;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 17.
DE SubName: Full=HEY1 protein {ECO:0000313|EMBL:NXM90002.1};
DE Flags: Fragment;
GN Name=Hey1 {ECO:0000313|EMBL:NXM90002.1};
GN ORFNames=OENOEN_R01140 {ECO:0000313|EMBL:NXM90002.1};
OS Oenanthe oenanthe (Northern wheatear).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Muscicapidae; Oenanthe.
OX NCBI_TaxID=279966 {ECO:0000313|EMBL:NXM90002.1, ECO:0000313|Proteomes:UP000565754};
RN [1] {ECO:0000313|EMBL:NXM90002.1, ECO:0000313|Proteomes:UP000565754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-74 {ECO:0000313|EMBL:NXM90002.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXM90002.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXM90002.1}.
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DR EMBL; VXBF01013321; NXM90002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L1EKH8; -.
DR Proteomes; UP000565754; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR FunFam; 4.10.280.10:FF:000079; CLUMA_CG001539, isoform A; 1.
DR Gene3D; 6.10.250.980; -; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR050370; HES_HEY.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00511; ORANGE; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000565754};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..49
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 71..103
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 138..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXM90002.1"
FT NON_TER 249
FT /evidence="ECO:0000313|EMBL:NXM90002.1"
SQ SEQUENCE 249 AA; 26869 MW; E0F47EC837E009E3 CRC64;
IIEKRRRDRI NNSLSELRRL VPSAFEKQGS AKLEKAEILQ MTVDHLKMLH TAGGKGYFDA
HALAMDYRSL GFRECLAEVA RYLSIIEGLD ASDPLRVRLV SHLNNYASQR EAASSAHTGI
GHIPWGSAFG HHPHIPHPLL LAQSGHGNTS STASSTEPHH QSRIAAPHAE TSSLRVPPNG
SVGPVLPVVT STTKLSPPLL SSMASLSAFP FSFGSFHLLS PNVLSPSTPT QPAALSKPYR
PWGTEIGAF
//
