ID A0A7L1GH61_9PICI Unreviewed; 432 AA.
AC A0A7L1GH61;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 16.
DE SubName: Full=VTNC protein {ECO:0000313|EMBL:NXN12409.1};
DE Flags: Fragment;
GN Name=Vtn {ECO:0000313|EMBL:NXN12409.1};
GN ORFNames=INDMAC_R01647 {ECO:0000313|EMBL:NXN12409.1};
OS Indicator maculatus (spotted honeyguide).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Coraciimorphae;
OC Piciformes; Indicatoridae; Indicator.
OX NCBI_TaxID=545262 {ECO:0000313|EMBL:NXN12409.1, ECO:0000313|Proteomes:UP000557230};
RN [1] {ECO:0000313|EMBL:NXN12409.1, ECO:0000313|Proteomes:UP000557230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-78 {ECO:0000313|EMBL:NXN12409.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXN12409.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXN12409.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VXBD01007210; NXN12409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L1GH61; -.
DR OrthoDB; 9898692at2759; -.
DR Proteomes; UP000557230; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0050840; F:extracellular matrix binding; IEA:TreeGrafter.
DR GO; GO:0005178; F:integrin binding; IEA:TreeGrafter.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:TreeGrafter.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:TreeGrafter.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00094; HX; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 2.110.10.10; Hemopexin-like domain; 2.
DR InterPro; IPR051298; Heme_transport/Cell_adhesion.
DR InterPro; IPR000585; Hemopexin-like_dom.
DR InterPro; IPR036375; Hemopexin-like_dom_sf.
DR InterPro; IPR018487; Hemopexin-like_repeat.
DR InterPro; IPR018486; Hemopexin_CS.
DR InterPro; IPR020436; SMB_chordata.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR22917; HEMOPEXIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22917:SF3; VITRONECTIN; 1.
DR Pfam; PF00045; Hemopexin; 3.
DR Pfam; PF01033; Somatomedin_B; 1.
DR PRINTS; PR00022; SOMATOMEDINB.
DR SMART; SM00120; HX; 4.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF50923; Hemopexin-like domain; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS00024; HEMOPEXIN; 2.
DR PROSITE; PS51642; HEMOPEXIN_2; 4.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000557230};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..432
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029677367"
FT DOMAIN 19..62
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT REPEAT 135..179
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 180..227
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 228..285
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 373..424
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REGION 86..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXN12409.1"
FT NON_TER 432
FT /evidence="ECO:0000313|EMBL:NXN12409.1"
SQ SEQUENCE 432 AA; 49669 MW; 277E793B0D7E1228 CRC64;
MRLLLPAVVL ALLATARAAE DSCEGRCDEG FKANRKCQCD ALCMYYQSCC SDYSTVCKAK
VTRGDVFALP EDDYLDYNLT VDFGTEAPPT PLSPEEPTPE PTLEPTLGPE EMLTELPSIT
TSWFEEEKPE ELCSRKPFDA FTDLKNGSLY AFRGRYFYEL DKTSVLPGYP KLISDFWGIE
GPIDAAFTRI NCQGKTYLFK GSQYWRFDDG SLDPGYPRNI SEGFEGIPNN VDAAFALPAH
NYHGNERVYF FKDKYYWSYD FAHQPTQADC EKSSPSTVFN HYAFMNRDSW EDVFQLLFGG
RMIGASSPRY ISRDWRGVPS RLDAAMAGRI YVASHHHRRR KSRRQRKRYK NHRSLNLGFW
GWLQNDSESA GVENDWLSGS KCDTLQSVYF FVGDKYYRVN LRTKRVDLVQ PRYPRSIAQY
WLHCPQPGEE SA
//
