ID A0A7L1JTD7_RYNNI Unreviewed; 423 AA.
AC A0A7L1JTD7;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE RecName: Full=Dynein axonemal assembly factor 4 {ECO:0000256|ARBA:ARBA00024430};
DE Flags: Fragment;
GN Name=Dnaaf4 {ECO:0000313|EMBL:NXN54108.1};
GN ORFNames=RYNNIG_R13979 {ECO:0000313|EMBL:NXN54108.1};
OS Rynchops niger (Black skimmer).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Laridae;
OC Rynchops.
OX NCBI_TaxID=227184 {ECO:0000313|EMBL:NXN54108.1, ECO:0000313|Proteomes:UP000525416};
RN [1] {ECO:0000313|EMBL:NXN54108.1, ECO:0000313|Proteomes:UP000525416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-16 {ECO:0000313|EMBL:NXN54108.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXN54108.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, neuron projection
CC {ECO:0000256|ARBA:ARBA00004487}. Dynein axonemal particle
CC {ECO:0000256|ARBA:ARBA00024190}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXN54108.1}.
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DR EMBL; VXBH01004048; NXN54108.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L1JTD7; -.
DR OrthoDB; 348005at2759; -.
DR Proteomes; UP000525416; Unassembled WGS sequence.
DR GO; GO:0120293; C:dynein axonemal particle; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:GOC.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030331; F:nuclear estrogen receptor binding; IEA:TreeGrafter.
DR GO; GO:0007368; P:determination of left/right symmetry; IEA:TreeGrafter.
DR GO; GO:0003351; P:epithelial cilium movement involved in extracellular fluid movement; IEA:TreeGrafter.
DR GO; GO:0007507; P:heart development; IEA:TreeGrafter.
DR GO; GO:0036159; P:inner dynein arm assembly; IEA:TreeGrafter.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0036158; P:outer dynein arm assembly; IEA:TreeGrafter.
DR CDD; cd06469; p23_DYX1C1_like; 1.
DR FunFam; 1.25.40.10:FF:000176; dynein assembly factor 4, axonemal isoform X1; 1.
DR FunFam; 2.60.40.790:FF:000015; dynein assembly factor 4, axonemal isoform X1; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR037894; CS_DYX1C1.
DR InterPro; IPR052004; Dynein_assembly_factor_4.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_rpt.
DR PANTHER; PTHR46492; DYNEIN ASSEMBLY FACTOR 4, AXONEMAL; 1.
DR PANTHER; PTHR46492:SF1; DYNEIN AXONEMAL ASSEMBLY FACTOR 4; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000525416};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 3..87
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REPEAT 369..402
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 105..198
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXN54108.1"
FT NON_TER 423
FT /evidence="ECO:0000313|EMBL:NXN54108.1"
SQ SEQUENCE 423 AA; 49059 MW; 7FA51CF20B500359 CRC64;
MPVWLREHRW WQTASAVYLS LPVRCLRVTA ANIFCTDRYL KVSIPPFLFE AILYAPIDDI
NSTAKIGNGM IFFTLYKKET AMWDSLTLAN ANKEKLQYLR ENAVLKAHEK AKEETEAKKV
TKQEHKKYAL EATMKLEETE RKRIEDLKEK ERQKVTKELE LWTKQQDAAE KHNRVQKEGE
LHQEVEQLKE KKKEKIKKTR IPNEGTSETR IKATKGRGSY SMFSENLKEE QLPAPRSTAT
IKINFTSRVF PTALRESRVA EEEEWLRKQA EARRTISDDL SELEDLKEEE KNPDWLKDKG
NKMFATGNYL AAVNAYNLAV RLNNKLPLLY LNRAACHLKL RNLHKAIEDS SKALELLTPP
VPDNENARIK AYVRRGTAFC QLELYAEGLQ DYEAALKIDP KNKNIEKDAE KIRHLIQGTT
QDS
//
