ID A0A7L1RU59_9PASS Unreviewed; 108 AA.
AC A0A7L1RU59;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 13.
DE RecName: Full=Transmembrane protein 14C {ECO:0000256|ARBA:ARBA00039421};
DE Flags: Fragment;
GN Name=Tmem14c_1 {ECO:0000313|EMBL:NXO40653.1};
GN ORFNames=LOCOCH_R01228 {ECO:0000313|EMBL:NXO40653.1};
OS Helopsaltes ochotensis (Middendorff's grasshopper-warbler).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Locustellidae; Helopsaltes.
OX NCBI_TaxID=3150915 {ECO:0000313|EMBL:NXO40653.1, ECO:0000313|Proteomes:UP000572057};
RN [1] {ECO:0000313|Proteomes:UP000572057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for normal heme biosynthesis.
CC {ECO:0000256|ARBA:ARBA00037428}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM14 family.
CC {ECO:0000256|ARBA:ARBA00007590}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXO40653.1}.
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DR EMBL; VXBM01000606; NXO40653.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L1RU59; -.
DR OrthoDB; 5620at2759; -.
DR Proteomes; UP000572057; Unassembled WGS sequence.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:TreeGrafter.
DR GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0070453; P:regulation of heme biosynthetic process; IEA:TreeGrafter.
DR FunFam; 1.10.10.1740:FF:000002; Transmembrane protein 14C; 1.
DR Gene3D; 1.10.10.1740; Transmembrane protein 14-like; 1.
DR InterPro; IPR005349; TMEM14.
DR InterPro; IPR044890; TMEM14_sf.
DR PANTHER; PTHR12668; TRANSMEMBRANE PROTEIN 14, 15; 1.
DR PANTHER; PTHR12668:SF4; TRANSMEMBRANE PROTEIN 14C-RELATED; 1.
DR Pfam; PF03647; Tmemb_14; 1.
PE 3: Inferred from homology;
KW Heme biosynthesis {ECO:0000256|ARBA:ARBA00023133};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000572057};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXO40653.1"
FT NON_TER 108
FT /evidence="ECO:0000313|EMBL:NXO40653.1"
SQ SEQUENCE 108 AA; 11110 MW; 0CC26C9937126FE0 CRC64;
PQMEYDWLGF GYAALVAAGG VAGYAKAGSV PSLAAGLLFG GLAGLGAYQQ SKDPKNVWLS
LVASGTLSAV MGMRFYNSKK AMPGIIAGAS LLMVGRLGLQ MMEKPIKP
//
