ID A0A7L2Q297_9PASS Unreviewed; 254 AA.
AC A0A7L2Q297;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 18.
DE RecName: Full=NAD(P)(+)--arginine ADP-ribosyltransferase {ECO:0000256|RuleBase:RU361228};
DE EC=2.4.2.31 {ECO:0000256|RuleBase:RU361228};
DE AltName: Full=Mono(ADP-ribosyl)transferase {ECO:0000256|RuleBase:RU361228};
DE Flags: Fragment;
GN Name=Nrt2_3 {ECO:0000313|EMBL:NXR90256.1};
GN ORFNames=HYPCIN_R03402 {ECO:0000313|EMBL:NXR90256.1};
OS Hypocryptadius cinnamomeus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Zosteropidae; Hypocryptadius.
OX NCBI_TaxID=589841 {ECO:0000313|EMBL:NXR90256.1, ECO:0000313|Proteomes:UP000574191};
RN [1] {ECO:0000313|EMBL:NXR90256.1, ECO:0000313|Proteomes:UP000574191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-83 {ECO:0000313|EMBL:NXR90256.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-
CC arginyl-[protein] + nicotinamide + H(+); Xref=Rhea:RHEA:19149,
CC Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:15087, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:29965, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:142554; EC=2.4.2.31;
CC Evidence={ECO:0000256|ARBA:ARBA00047597,
CC ECO:0000256|RuleBase:RU361228};
CC -!- SIMILARITY: Belongs to the Arg-specific ADP-ribosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009558, ECO:0000256|RuleBase:RU361228}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXR90256.1}.
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DR EMBL; VYZP01036050; NXR90256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L2Q297; -.
DR OrthoDB; 423533at2759; -.
DR Proteomes; UP000574191; Unassembled WGS sequence.
DR GO; GO:0044194; C:cytolytic granule; IEA:UniProtKB-ARBA.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-ARBA.
DR GO; GO:0003950; F:NAD+ poly-ADP-ribosyltransferase activity; IEA:TreeGrafter.
DR GO; GO:0106274; F:NAD+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-ARBA.
DR FunFam; 3.90.176.10:FF:000001; NAD(P)(+)--arginine ADP-ribosyltransferase; 1.
DR Gene3D; 3.90.176.10; Toxin ADP-ribosyltransferase, Chain A, domain 1; 1.
DR InterPro; IPR050999; ADP-ribosyltransferase_ARG.
DR InterPro; IPR000768; ART.
DR PANTHER; PTHR10339; ADP-RIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR10339:SF19; GPI-LINKED NAD(P)(+)--ARGININE ADP-RIBOSYLTRANSFERASE 1; 1.
DR Pfam; PF01129; ART; 1.
DR PRINTS; PR00970; RIBTRNSFRASE.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR PROSITE; PS01291; ART; 1.
DR PROSITE; PS51996; TR_MART; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU361228};
KW NAD {ECO:0000256|ARBA:ARBA00023027, ECO:0000256|RuleBase:RU361228};
KW NADP {ECO:0000256|ARBA:ARBA00022857, ECO:0000256|RuleBase:RU361228};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000574191};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361228};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361228}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|RuleBase:RU361228"
FT CHAIN 25..254
FT /note="NAD(P)(+)--arginine ADP-ribosyltransferase"
FT /evidence="ECO:0000256|RuleBase:RU361228"
FT /id="PRO_5029939623"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXR90256.1"
FT NON_TER 254
FT /evidence="ECO:0000313|EMBL:NXR90256.1"
SQ SEQUENCE 254 AA; 29112 MW; C01D0100B62023A1 CRC64;
WPHPAMALLA RTLALLAMTV ATVAIKVVPL DMAQNSFDDQ YRGCGHAMTA VLPALNNIEF
QKNPHFAKGW AVAQAEWRKQ GSPVSPLASP AQAVALMAYT MQHLYKDFNA AVRTAGRSRQ
EYRNNFHFKT LHFLLTKALM TLRHAQNEQC HRVFRGVRDV RFQARRGQRV RFGQFTSTSQ
RKEIALHFGT DTIFEVHTCH GAAIRQFSMY PWEEEVLIPP FETFKVTKVT RNGKRTRISL
RSEGTFSKYN CEWL
//
