ID A0A7L3Q8E5_9SYLV Unreviewed; 813 AA.
AC A0A7L3Q8E5;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE SubName: Full=AFF3 protein {ECO:0000313|EMBL:NXU99614.1};
DE Flags: Fragment;
GN Name=Aff3_0 {ECO:0000313|EMBL:NXU99614.1};
GN ORFNames=CETCET_R00956 {ECO:0000313|EMBL:NXU99614.1};
OS Cettia cetti.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Sylviidae; Acrocephalinae; Cettia.
OX NCBI_TaxID=68486 {ECO:0000313|EMBL:NXU99614.1, ECO:0000313|Proteomes:UP000524451};
RN [1] {ECO:0000313|EMBL:NXU99614.1, ECO:0000313|Proteomes:UP000524451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUT-0056 {ECO:0000313|EMBL:NXU99614.1};
RC TISSUE=Blood {ECO:0000313|EMBL:NXU99614.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXU99614.1}.
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DR EMBL; VZUI01034615; NXU99614.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L3Q8E5; -.
DR Proteomes; UP000524451; Unassembled WGS sequence.
DR GO; GO:0016607; C:nuclear speck; IEA:TreeGrafter.
DR GO; GO:0002151; F:G-quadruplex RNA binding; IEA:TreeGrafter.
DR GO; GO:0043484; P:regulation of RNA splicing; IEA:TreeGrafter.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR InterPro; IPR043639; AF4_int.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF18; AF4_FMR2 FAMILY MEMBER 2; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18875; AF4_int; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000524451}.
FT DOMAIN 550..812
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 1..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..104
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..445
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..498
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..731
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXU99614.1"
FT NON_TER 813
FT /evidence="ECO:0000313|EMBL:NXU99614.1"
SQ SEQUENCE 813 AA; 89368 MW; CC3240381DE543DF CRC64;
VPSSSLPVPV AHATLAHSSG GSGSSSESES SSESDSDSES SSSDSECNEE SRSATPEPEP
PSTNKWQLDK WLNKVNPHNK TIINNQNEPH SESSSQAQSN QQAEGPNKGK LNSSLPPTDP
KERAILSPIR EKAKPRVAQK TPEAKSSKQK SPAHNEPTSQ RTTGKKQPKK VERTSSVEEY
NWPKPNNTSN TPKEKDTQEP PEQPKVRTKA AVGKTAPRKE PRTSTGLTSE KKKYRGPSKI
VPKSREFIET DSSTSDSNTD QEESLQAKVL PACTGSGSGV KVKDSGSNIL SVSSLTSNGS
NTSIDQTSND LEEQLFSPIP IVQNELLSPL REYEELKSLW VKIDLSLLSR IPGQETFETT
SVKSEPREAN VKHRRPSRES PTPAAEKPST KSKRKHKTES LDTFVESKKP RLEEPPASCL
LPPCISPIPN HRITSTKESS SSSVKKVTKK REEKLFPPPL SPLLDDPVHR RHSSDSSSFS
QEPTVTNTSQ TSSSSSSASK HRKNENKSSS NPKGICEEEP HSTPTANTLL DTSHLEPDIW
SAMPMLSNGN SEPRRPKITF DDVLHNADYY MQEAKKLKHK ADALLEKFGK AVNYADAALS
FIECGNAMER DPLEAKSPYT MYSETVELIR YAMRLKNFTG SSATEGDKKL AVLCYRCLSL
LYLRMFKLKK DHAMKYSRSL MEYFKNSSKA SQAPSPWGGN GKSTETPSPM SLSPSPVSSA
GSSAGSAGSS SAGTITIPQR IHHMAASHVN ITNNVLRSYE HWDMADKLAK ENKEFFVDLD
SVMGPLTQHS SMTSLVRYVR QGLHWLRIEA HLL
//
