ID A0A7L3QQ83_9SYLV Unreviewed; 510 AA.
AC A0A7L3QQ83;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 17.
DE SubName: Full=FOXP1 protein {ECO:0000313|EMBL:NXV03399.1};
DE Flags: Fragment;
GN Name=Foxp1 {ECO:0000313|EMBL:NXV03399.1};
GN ORFNames=CETCET_R01396 {ECO:0000313|EMBL:NXV03399.1};
OS Cettia cetti.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Sylviidae; Acrocephalinae; Cettia.
OX NCBI_TaxID=68486 {ECO:0000313|EMBL:NXV03399.1, ECO:0000313|Proteomes:UP000524451};
RN [1] {ECO:0000313|EMBL:NXV03399.1, ECO:0000313|Proteomes:UP000524451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUT-0056 {ECO:0000313|EMBL:NXV03399.1};
RC TISSUE=Blood {ECO:0000313|EMBL:NXV03399.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXV03399.1}.
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DR EMBL; VZUI01047515; NXV03399.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L3QQ83; -.
DR Proteomes; UP000524451; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20065; FH_FOXP2; 1.
DR FunFam; 1.20.5.340:FF:000005; Forkhead box P1, isoform CRA_f; 1.
DR FunFam; 1.10.10.10:FF:000010; Forkhead box P2 isoform B; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047412; FH_FOXP1_P2.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050998; FOXP.
DR InterPro; IPR032354; FOXP-CC.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45796; FORKHEAD BOX P, ISOFORM C; 1.
DR PANTHER; PTHR45796:SF3; FORKHEAD BOX PROTEIN P1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF16159; FOXP-CC; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000524451};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 298..371
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 298..371
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 104..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..251
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..510
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXV03399.1"
FT NON_TER 510
FT /evidence="ECO:0000313|EMBL:NXV03399.1"
SQ SEQUENCE 510 AA; 56817 MW; 995F6F7AC939A11E CRC64;
QPQQQQVATQ QLAFQQQLLQ MQQLQQQHLL SLQRQGLLTI QPGQPTLPLQ PLAQGMIPTE
LQQLWKEVTS SHTAEEAASN NHSSLDLSTT CVSSSAPSKT SLIINPHAST NGQLSVHTPK
RESLSHEEHS HSHPLYGHGV CKWPGCEAVC EDFQSFLKHL NSEHALDDRS TAQCRVQMQV
VQQLELQLAK DKERLQAMMT HLHVKSTEPK ATPQPLNLVS SVTLSKTASE ASPQSLPHTP
TTPTAPITPV TQGPSVITTT SMHSVGPIRR RYSDKYNVPI SSADIAQNQE FYKNAEVRPP
FTYASLIRQA ILESPEKQLT LNEIYNWFTR MFAYFRRNAA TWKNAVRHNL SLHKCFVRVE
NVKGAVWTVD ELEFQKRRPQ KISGNPSLIK NIQTSHTYCT PLNAALQASM AENSIPLYTT
ASMGNPTLGN LASAMREELN GAMEHTNSNG SDSSPGRSPM QAMHPVHVKE EPLDPDENEG
PLSLVTTANH SPDFDHDRDY EDEPVNEDIE
//
