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Database: UniProt
Entry: A0A7L3QU33_9SYLV
LinkDB: A0A7L3QU33_9SYLV
Original site: A0A7L3QU33_9SYLV 
ID   A0A7L3QU33_9SYLV        Unreviewed;       117 AA.
AC   A0A7L3QU33;
DT   07-APR-2021, integrated into UniProtKB/TrEMBL.
DT   07-APR-2021, sequence version 1.
DT   18-JUN-2025, entry version 11.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 11 {ECO:0000256|ARBA:ARBA00019621, ECO:0000256|RuleBase:RU364147};
DE   AltName: Full=Mediator complex subunit 11 {ECO:0000256|ARBA:ARBA00032011, ECO:0000256|RuleBase:RU364147};
DE   Flags: Fragment;
GN   Name=Med11 {ECO:0000313|EMBL:NXV06986.1};
GN   Synonyms=MED11 {ECO:0000256|RuleBase:RU364147};
GN   ORFNames=CETCET_R15026 {ECO:0000313|EMBL:NXV06986.1};
OS   Cettia cetti.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC   Passeriformes; Sylvioidea; Sylviidae; Acrocephalinae; Cettia.
OX   NCBI_TaxID=68486 {ECO:0000313|EMBL:NXV06986.1, ECO:0000313|Proteomes:UP000524451};
RN   [1] {ECO:0000313|EMBL:NXV06986.1, ECO:0000313|Proteomes:UP000524451}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OUT-0056 {ECO:0000313|EMBL:NXV06986.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:NXV06986.1};
RA   Zhang G.;
RT   "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional pre-initiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|RuleBase:RU364147}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364147}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364147}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 11 family.
CC       {ECO:0000256|ARBA:ARBA00008186, ECO:0000256|RuleBase:RU364147}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:NXV06986.1}.
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DR   EMBL; VZUI01067734; NXV06986.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A7L3QU33; -.
DR   Proteomes; UP000524451; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   FunFam; 1.10.287.3490:FF:000001; Mediator of RNA polymerase II transcription subunit 11; 1.
DR   Gene3D; 1.10.287.3490; -; 1.
DR   InterPro; IPR019404; Mediator_Med11.
DR   PANTHER; PTHR22890; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11; 1.
DR   Pfam; PF10280; Med11; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|RuleBase:RU364147};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364147};
KW   Reference proteome {ECO:0000313|Proteomes:UP000524451};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU364147};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU364147}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:NXV06986.1"
FT   NON_TER         117
FT                   /evidence="ECO:0000313|EMBL:NXV06986.1"
SQ   SEQUENCE   117 AA;  12911 MW;  ED821189DB45AB89 CRC64;
     MAGFGVANER LRALEELERE IGASLQSAGS VILELSKEKP QERHLDRQAA QFGAAVAKVE
     AELSAQIRYL TQVATGQPHE GSSYAARKSC QLALNRLDYA RRRLAELARA CELMLEQ
//
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