UniProt: A0A7L3W9F6

Database: UniProt
Entry: A0A7L3W9F6_9GRUI

LinkDB:  A0A7L3W9F6_9GRUI 
Original site:  A0A7L3W9F6_9GRUI

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Ontology (5)   
   GO (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (9)   
   InterPro (5)   
   Pfam (1)   
   PROSITE (2)   
   SMART (1)   
All databases (16)   

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ID   A0A7L3W9F6_9GRUI        Unreviewed;       328 AA.
AC   A0A7L3W9F6;
DT   07-APR-2021, integrated into UniProtKB/TrEMBL.
DT   07-APR-2021, sequence version 1.
DT   18-JUN-2025, entry version 16.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE   Flags: Fragment;
GN   Name=Rnf19b_0 {ECO:0000313|EMBL:NXV72793.1};
GN   ORFNames=ATLROG_R02210 {ECO:0000313|EMBL:NXV72793.1};
OS   Atlantisia rogersi (Inaccessible Island rail).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Neoaves; Gruiformes; Rallidae; Atlantisia.
OX   NCBI_TaxID=2478892 {ECO:0000313|EMBL:NXV72793.1, ECO:0000313|Proteomes:UP000518911};
RN   [1] {ECO:0000313|EMBL:NXV72793.1, ECO:0000313|Proteomes:UP000518911}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OUT-0055 {ECO:0000313|EMBL:NXV72793.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:NXV72793.1};
RA   Zhang G.;
RT   "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:NXV72793.1}.
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DR   EMBL; VZUJ01051180; NXV72793.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A7L3W9F6; -.
DR   OrthoDB; 1431934at2759; -.
DR   Proteomes; UP000518911; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd20338; BRcat_RBR_RNF19; 1.
DR   CDD; cd20355; Rcat_RBR_RNF19; 1.
DR   FunFam; 1.20.120.1750:FF:000017; RBR-type E3 ubiquitin transferase; 1.
DR   FunFam; 3.30.40.10:FF:000424; RBR-type E3 ubiquitin transferase; 1.
DR   Gene3D; 1.20.120.1750; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   Pfam; PF01485; IBR; 2.
DR   SMART; SM00647; IBR; 2.
DR   SUPFAM; SSF57850; RING/U-box; 3.
DR   PROSITE; PS51873; TRIAD; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:NXV72793.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000518911};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   TRANSMEM        232..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..222
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   DOMAIN          2..49
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          138..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:NXV72793.1"
FT   NON_TER         328
FT                   /evidence="ECO:0000313|EMBL:NXV72793.1"
SQ   SEQUENCE   328 AA;  35729 MW;  FCBAB2A3F8C02422 CRC64;
     ECPLCLLPQP PEAFPSLASC EHRSCRACLE QYLRIAVTES RVQLACPHCP AALQPADLHR
     LLEPALRHKY EEFLLRRLLV ADPGTRWCPA PDCSYAVIAY GCAECPRLTC GREGCGTEFC
     YHCRQPWHPD RPCVPALPAP SPSDPTARPA HPEDSAHGET PAQAEPEAIK VCPRCSAFIM
     KINDGSCNRM SCTVCGCLFC WLCLREISDV HFLSPSGCTF WGKRPWSRTR KILWQLGMVL
     GAPMVISLIA GIAVPVITVG IPIYMGRKVL TGHLGSPCLS GCQQCLSVTS SVLLSLFVSP
     IITAVTVGVG VPLMLTYVYG VVVLSLCR
//

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