ID A0A7L4EVU6_HIRRU Unreviewed; 530 AA.
AC A0A7L4EVU6;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 16.
DE SubName: Full=FOXK1 protein {ECO:0000313|EMBL:NXW78850.1};
DE Flags: Fragment;
GN Name=Foxk1 {ECO:0000313|EMBL:NXW78850.1};
GN ORFNames=HIRRUS_R14107 {ECO:0000313|EMBL:NXW78850.1};
OS Hirundo rustica (Barn swallow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Hirundinidae; Hirundo.
OX NCBI_TaxID=43150 {ECO:0000313|EMBL:NXW78850.1, ECO:0000313|Proteomes:UP000585317};
RN [1] {ECO:0000313|EMBL:NXW78850.1, ECO:0000313|Proteomes:UP000585317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-67 {ECO:0000313|EMBL:NXW78850.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXW78850.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXW78850.1}.
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DR EMBL; VZZX01010743; NXW78850.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L4EVU6; -.
DR Proteomes; UP000585317; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR CDD; cd20054; FH_FOXK1; 1.
DR FunFam; 1.10.10.10:FF:000030; Forkhead box protein K2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047394; FH_FOXK1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45881; CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR45881:SF4; FORKHEAD BOX PROTEIN K1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 123..218
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 123..218
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 231..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..496
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXW78850.1"
FT NON_TER 530
FT /evidence="ECO:0000313|EMBL:NXW78850.1"
SQ SEQUENCE 530 AA; 56306 MW; 701B375A7DA2F611 CRC64;
RCTFRFPSTV IKIQFTSLYH KEEVKEEAST HPLRPLYPQI SPLKIHIPEP DLRSVVSPLP
SPTGTISVPN SCPASPRGAG SSGYRFVHNI TSDLQLAAEY AAKAASEQQA DASGGDSPKD
ESKPPYSYAQ LIVQAISSAQ DRQLTLSGIY AHITKHYPYY RTADKGWQNS IRHNLSLNRY
FIKVPRSQEE PGKGSFWRID PASEAKLVEQ AFRKRRQRGV SCFRTPFGPL SSRSAPASPT
HPGLLSPRSS GLQTPECLSR EGSPIPHDHD FGSKLASVPE YRYSQSAPGS PVSAQPVIMA
VPPRPSTLVA KPVAYMPASI VTSQQPPCHA IHVVQQAPTV TMVRVVTSSA NSANGYILTN
QGTAGGAHEA AGAVLDLAGD HRGMDEKPTI AFATIPTASR VIQTVASQMA QGVPGQTVTI
LQQAAPVALG QHQLPVRAVT QNGKHAVPTN SIAGSAYALT NPLQLLAAQA SSSTPVVVSR
VCEPGTEETA AASSSEPEVK RARIEEPSGA VPAQTGVITS TVPQGQATSE
//
