ID A0A7L4HD05_PODST Unreviewed; 1109 AA.
AC A0A7L4HD05;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE RecName: Full=Ankyrin repeat and IBR domain-containing protein 1 {ECO:0000256|ARBA:ARBA00069741};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
DE Flags: Fragment;
GN Name=Ankib1 {ECO:0000313|EMBL:NXX23205.1};
GN ORFNames=PODSTR_R08302 {ECO:0000313|EMBL:NXX23205.1};
OS Podargus strigoides (Tawny frogmouth) (Caprimulgus strigoides).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Strisores; Caprimulgiformes;
OC Podargidae; Podargus.
OX NCBI_TaxID=8905 {ECO:0000313|EMBL:NXX23205.1, ECO:0000313|Proteomes:UP000584326};
RN [1] {ECO:0000313|EMBL:NXX23205.1, ECO:0000313|Proteomes:UP000584326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-40 {ECO:0000313|EMBL:NXX23205.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXX23205.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXX23205.1}.
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DR EMBL; VZTK01029674; NXX23205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L4HD05; -.
DR OrthoDB; 69641at2759; -.
DR Proteomes; UP000584326; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20346; BRcat_RBR_ANKIB1; 1.
DR CDD; cd20361; Rcat_RBR_ANKIB1; 1.
DR CDD; cd16774; RING-HC_RBR_ANKIB1; 1.
DR FunFam; 1.20.120.1750:FF:000003; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 1.25.40.20:FF:000040; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000129; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR047564; Rcat_RBR_ANKIB1.
DR InterPro; IPR047563; RING-HC_RBR_ANKIB1.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000584326};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 345..585
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 349..395
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 297..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1006..1031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..334
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..977
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1071..1101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXX23205.1"
FT NON_TER 1109
FT /evidence="ECO:0000313|EMBL:NXX23205.1"
SQ SEQUENCE 1109 AA; 124678 MW; A9CE6A058B514228 CRC64;
NMGNTTTKFR KALINGDENL ACQIYESNPQ LKETLDPNTS YGETYQHNTP LHYAARHGMN
RILGTFLFVR DGNPNKRNVH NETSMHLLCM GPQIMISEGA LHPRLTRPSE DDCRRADCLQ
MILKWKGAKL DEGQYERAAI DAVDNKKNTP LHYAAASGMK TCVELVIVNC LLCRFTCNCL
VKHGGDLFAE NENKDTPCDC AEKQHHKELA LNLESRMVFS RDPEAESIEA EYAALDKKEP
YEGLRLQDLR RLKDMLIVES ADMLQAPLFT AEALLRAHDW DREKLLEAWM SNPENCCQRS
GVQMPTPPPS GYNAWDTLPS PRTPRTTRSS VTSPDEISPS PGDIDTAVCD ICMCNISVFE
DPVDMPCGHD FCRACWEAFL NLKIQEGEAH NIFCPAYECF QLVPVDIIES VVSKEMDKRY
LQFDIKAFVE NNPAIKWCPI PGCERAVRLT RQGSNSTGSD TLSFPMLKAP AVDCGKGHLF
CWECLGEAHE PCDCQTWKDW LQKISEMKPE ELVGVSEAYE DAANCLWLLT NSKPCANCKS
PIQKNEGCNH MQCAKCKYDF CWICLEEWKK HSSSTGGYYR CTRYEVIQHV EEQSKEMTVE
AEKKHRRFQE LDRFMHYYTR FKNHELSYQL EQRLLKTAKE KMEQLSRALS GTEGGCPDTT
FIEDAVHELL KTRRILKCSY PYGFFLEPKS TKKEIFELMQ TDLEMVTEDL AQKVNRPYLR
TPRHKIIRAA CLVQQKRQEF LASVARGVAP ADSPEAPRRS FAGGTWDWEY LGFASPEEYA
EFQYRRRHRQ RRRGDMHSLL SNTPDPDDPS ESTLDTQEGG SSRRHGTSMV SSASMGILHS
SSLHDYTPVS RSENQDSLQA LSSLDEDDPN ILLAIQLSLQ ESGLAIDEET RDFLNNEASL
GAIGTSLPTR LDSAPISIDN PRGALSSSEL LELGDSLMRL GAGNDPFSAD RLHSHPCSDT
RSGLYSTSSD ADSSSQDPNT NENLLGNIMA WFHDMNPQSI ALIPSTSTET DEDSQQPSTE
DGSAGQPNLI DTGLEPQEEH ALFEDALKNE GRGTQTEEGT SEENVIPGEI VSQSSDNNRE
VTSTLDASGD TSSQTPQTSS EWIEHVRLV
//
