ID A0A7L4HKD1_SCOUM Unreviewed; 322 AA.
AC A0A7L4HKD1;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=BBSome complex member BBS5 {ECO:0000256|ARBA:ARBA00047191};
DE Flags: Fragment;
GN Name=Bbs5 {ECO:0000313|EMBL:NXX53083.1};
GN ORFNames=SCOUMB_R00478 {ECO:0000313|EMBL:NXX53083.1};
OS Scopus umbretta (Hammerkop).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes;
OC Scopidae; Scopus.
OX NCBI_TaxID=33581 {ECO:0000313|EMBL:NXX53083.1, ECO:0000313|Proteomes:UP000539032};
RN [1] {ECO:0000313|EMBL:NXX53083.1, ECO:0000313|Proteomes:UP000539032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-70 {ECO:0000313|EMBL:NXX53083.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXX53083.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXX53083.1}.
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DR EMBL; VZTL01006683; NXX53083.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7L4HKD1; -.
DR OrthoDB; 10261999at2759; -.
DR Proteomes; UP000539032; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR CDD; cd00900; PH-like; 1.
DR FunFam; 2.30.29.30:FF:000232; Bardet-Biedl syndrome 5 isoform 1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR030804; BBS5/fem-3.
DR InterPro; IPR014003; BBS5_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR PIRSF; PIRSF010072; DUF1448; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000539032}.
FT DOMAIN 9..63
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 139..193
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXX53083.1"
FT NON_TER 322
FT /evidence="ECO:0000313|EMBL:NXX53083.1"
SQ SEQUENCE 322 AA; 36854 MW; 264A65367880E44D CRC64;
RQMKMRPGEV LIDCLESVED TKGNNGDRGR LLVTNLRIIW RSLSLPRVNL SVGYNCIINI
TTRTANSKLR GQTEALYILT KCNNTRFEFI FTNVVPGSPR LFTSVIAVHR AYETSKMYRD
LKLRSALIQN KQLRLLPQEQ IYDKINGVWN LSSDQGNLGT FFVTNVRIVW HANMNDSFNV
SIPYLQIRSI KIRDSKFGLA LVIESSQQSG GYVLGFKIDP VEKLQEAVKE INSLHRVYSA
NPIFGVDYEM EEKPQPLEDL TVEQVQDDVE IESDEHTDAF VAYFADENKQ HDREPVFSEE
LGLAIEKLKD GFTLQGLWEV MT
//
