ID A0A7M7II01_APIME Unreviewed; 986 AA.
AC A0A7M7II01; A0A8B7KPA0;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Collagen alpha-2(IX) chain isoform X11 {ECO:0000313|RefSeq:XP_016770398.1};
GN Name=LOC412865 {ECO:0000313|RefSeq:XP_016770398.1};
OS Apis mellifera (Honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=7460 {ECO:0000313|EnsemblMetazoa:XP_016770398};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_016770398}
RP IDENTIFICATION.
RC STRAIN=DH4 {ECO:0000313|EnsemblMetazoa:XP_016770398};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_016770398.1}
RP IDENTIFICATION.
RC STRAIN=DH4 {ECO:0000313|RefSeq:XP_016770398.1};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_016770398.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016770398.1; XM_016914909.2.
DR AlphaFoldDB; A0A7M7II01; -.
DR EnsemblMetazoa; XM_016914909; XP_016770398; LOC412865.
DR GeneID; 412865; -.
DR CTD; 104327; -.
DR OrthoDB; 5983381at2759; -.
DR Proteomes; UP000005203; Linkage group LG11.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF914; OTOLIN-1; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119,
KW ECO:0000313|RefSeq:XP_016770398.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005203}.
FT DOMAIN 697..745
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 786..951
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 55..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..367
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..412
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..499
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..552
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..586
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..607
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 964..973
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 986 AA; 102126 MW; 41CDB63B720E4170 CRC64;
MTNHVYRAIV YYFLIVYLKG LLQSLKLYPG HPADLVKCTA DFNFDQDVDL GSGEIDNEVI
DNGSGFDINL TDIGRDDDED RSEESNPPPF ITPPPPNPDY KGPKGEKGDK GDKGESVRGP
PGPPGPPGQD EGPPGKKGEP GTCTCNATAL MASFTMPKMI QGPKGEQGVP GQEGKQGQMG
LTGVAGPPGE RGLEGPQGPK GDKGDVGIPG PEGPQGQKGE PGRDGIPGEK GAQGPPGPPG
KGEFSGYDPS WKPRGIYRTE GITMRPGLPG QKGEAGLPGS PGPKGETGIA GAKGNKGEPG
HKGAKGDHGN EGARGIQGSK GEPGAPGAPG LPGAPGENGR PAEKGDKGDT GPEGKPGPPG
APGPPGLPGL SGPGGVNVGE SMLREKGDKG EGGARGYKGD KGTKGEKGDK GDSGPAGIPG
VNGIQGPQGN KGEPGKDGVA GVQGIAGAKG EKGERGPPGA TAIASSGDYI TIKGEKGAEG
KRGRRGRPGP PGPVGPPGKP GAMGEIGLPG WVNTMKGRPG TPGLPGPVGP AGPKGEKGEP
GTPSPYGVSV GVKGDKGDDG FPGIPGQPGR EGQRGPPGPP GPPGPPSQGN YIPVPGPPGP
PGPPGPPGLS LIGQKGEPGI GRSHIFGERD YYGVRQVQSV KKKHIPYPTL QGPRTSLDEL
KALRELKQLK ELKEHLGAGT TATRGPLEST TKIVPGAVTF QNTEAMTKMS AVSPVGTLAY
IIDEQALLVR VNNGWQYIAL GSLLPITTPA PPTTSPPPVN PPFEASNLIN QIPVKADGTG
WYPRMLRMAA LNEPFTGDMH GVRGADYACY RQAKRAGLRG TFRAFLSSRV QNVDSIVRLG
DRDLPIVNIK GDVLFNSWKE MFNGNGAYFS QNPRIYSFNG KNILTDFAWP EKVAWHGSHK
LGDRAMDTYC DAWHSSSSDR YGLGSPLTGG RLLEQVRYSC DNKFALLCIE VTSETTRRRR
NAEIAEDEDE MSENDYKEYL DSLMED
//
