ID A0A7M7IKF1_APIME Unreviewed; 1006 AA.
AC A0A7M7IKF1; A0A8B7KN61;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Collagen alpha-1(I) chain isoform X10 {ECO:0000313|RefSeq:XP_016770397.1};
GN Name=LOC412865 {ECO:0000313|RefSeq:XP_016770397.1};
OS Apis mellifera (Honeybee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Apis.
OX NCBI_TaxID=7460 {ECO:0000313|EnsemblMetazoa:XP_016770397};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_016770397}
RP IDENTIFICATION.
RC STRAIN=DH4 {ECO:0000313|EnsemblMetazoa:XP_016770397};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_016770397.1}
RP IDENTIFICATION.
RC STRAIN=DH4 {ECO:0000313|RefSeq:XP_016770397.1};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_016770397.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016770397.1; XM_016914908.2.
DR AlphaFoldDB; A0A7M7IKF1; -.
DR EnsemblMetazoa; XM_016914908; XP_016770397; LOC412865.
DR GeneID; 412865; -.
DR CTD; 104327; -.
DR OrthoDB; 5983381at2759; -.
DR Proteomes; UP000005203; Linkage group LG11.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF914; OTOLIN-1; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119,
KW ECO:0000313|RefSeq:XP_016770397.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005203};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 717..765
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 806..971
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 75..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..118
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..387
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..519
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..572
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..606
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..627
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..993
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 103915 MW; 257FD144DC2D02EF CRC64;
MAMVISPRSK IVTLSLLIGI ITVVAFIVTV IGIWHKSEKP GKTGTKVVSS KLQQITGYTA
TKHFDQDVDL GSGEIDNEVI DNGSGFDINL TDIGRDDDED RSEESNPPPF ITPPPPNPDY
KGPKGEKGDK GDKGESVRGP PGPPGPPGQD EGPPGKKGEP GTCTCNATAL MASFTMPKMI
QGPKGEQGVP GQEGKQGQMG LTGVAGPPGE RGLEGPQGPK GDKGDVGIPG PEGPQGQKGE
PGRDGIPGEK GAQGPPGPPG KGEFSGYDPS WKPRGIYRTE GITMRPGLPG QKGEAGLPGS
PGPKGETGIA GAKGNKGEPG HKGAKGDHGN EGARGIQGSK GEPGAPGAPG LPGAPGENGR
PAEKGDKGDT GPEGKPGPPG APGPPGLPGL SGPGGVNVGE SMLREKGDKG EGGARGYKGD
KGTKGEKGDK GDSGPAGIPG VNGIQGPQGN KGEPGKDGVA GVQGIAGAKG EKGERGPPGA
TAIASSGDYI TIKGEKGAEG KRGRRGRPGP PGPVGPPGKP GAMGEIGLPG WVNTMKGRPG
TPGLPGPVGP AGPKGEKGEP GTPSPYGVSV GVKGDKGDDG FPGIPGQPGR EGQRGPPGPP
GPPGPPSQGN YIPVPGPPGP PGPPGPPGLS LIGQKGEPGI GRSHIFGERD YYGVRQVQSV
KKKHIPYPTL QGPRTSLDEL KALRELKQLK ELKEHLGAGT TATRGPLEST TKIVPGAVTF
QNTEAMTKMS AVSPVGTLAY IIDEQALLVR VNNGWQYIAL GSLLPITTPA PPTTSPPPVN
PPFEASNLIN QIPVKADGTG WYPRMLRMAA LNEPFTGDMH GVRGADYACY RQAKRAGLRG
TFRAFLSSRV QNVDSIVRLG DRDLPIVNIK GDVLFNSWKE MFNGNGAYFS QNPRIYSFNG
KNILTDFAWP EKVAWHGSHK LGDRAMDTYC DAWHSSSSDR YGLGSPLTGG RLLEQVRYSC
DNKFALLCIE VTSETTRRRR NAEIAEDEDE MSENDYKEYL DSLMED
//
