ID A0A7M7IRT6_NASVI Unreviewed; 1156 AA.
AC A0A7M7IRT6;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 18.
DE RecName: Full=Thrombospondin-like N-terminal domain-containing protein {ECO:0000259|SMART:SM00210};
OS Nasonia vitripennis (Parasitic wasp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia.
OX NCBI_TaxID=7425 {ECO:0000313|EnsemblMetazoa:XP_016838935, ECO:0000313|Proteomes:UP000002358};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_016838935}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
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DR RefSeq; XP_016838935.1; XM_016983446.3.
DR AlphaFoldDB; A0A7M7IRT6; -.
DR SMR; A0A7M7IRT6; -.
DR EnsemblMetazoa; XM_016983446; XP_016838935; LOC100120859.
DR GeneID; 100120859; -.
DR CTD; 104327; -.
DR OrthoDB; 5983381at2759; -.
DR Proteomes; UP000002358; Chromosome 3.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN TRIPLE HELIX REPEAT; 1.
DR Pfam; PF01391; Collagen; 5.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000002358};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1156
FT /note="Thrombospondin-like N-terminal domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029471189"
FT DOMAIN 32..228
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT REGION 246..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..292
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..399
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..557
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..666
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..710
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..790
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..814
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1139
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1156 AA; 121215 MW; D835A5180BEE195D CRC64;
MSPNFRGSLP PLLLLLLLLL CAAARASQDF FGDKKETEFD LLEAAVSLID DKNLYLTDGY
DGFMSFGFRP GSEVKQPYRM YLPEKLPSEF TLVASFKPFS AKNSYLFAVL NPFETVVQLG
IRISDGPSTN QNISLIYTNS DMSTVSDEVA KFTVPRLVKR WSKIVIRVTP NEVILYLNCH
EMARQKVTRI PLELVFDTAS TLYIAQAGPH IQEKYDGLLQ SLKLHLGFPQ DLVKCNEDFD
FYSGGDGSGD HELISGSGEI DPDDVPIARG DDEVESEEVK PPPLITPPPP NPNSKEVTKG
EKGDKGEKGE SVRGPPGPPG TSYDLNDEEW IAKLPEGPPG PKGDPGDCSC NASALLTSFS
MPKLMHGEKG EPGTPGKEGK QGPLGLTGAA GPPGERGQPG PQGPKGDKGD LGNTGPEGSQ
GEKGEPGRDG APGEKGAQGP PGPPGKGEFA GYDPSWKPRA IYRTEGYAMR PGLPGQKGDD
GKPGHPGPKG EPGVHGAKGD KGDAGHKGMK GLHGKEGPRG VQGVKGEPGA PGVPGLPGAV
GEVGRTGDKG AKGDMGPEGK TGPAGPPGPP GHGGVSVSDV VGPGRGQKGE PGERGYKGDL
GLKGEKGDKG DFGPAGVPGI NGIQGPQGDK GEPGKDGSPG FPGTPGMKGE RGERGPPGAT
TIAGTGDYVT IKGEQGAMGP MGKRGRRGRP GPPGNEGPPG PPGPEGPPGK PGINGEIGLP
GWMNNMKGRP GTPGIPGLSG SKGEKGEPGA PSPYGSAHGI KGDKGADGFP GIPGAPGMRG
PPGPAGPPGV PSQGSYIPVP GPPGPPGPPG PPGPGIGKSH IYGERDYYGS RQGANAAATR
GPLETTTKIV PGAVTFQNTE AMTKMSGVSP VGTLAYIIDE QALLVRVNNG WQYIPLGTLL
PITTPAPPTT ASPPVNPPFE ASNLINQVPV KADGTSWYPK MLRMAALNEP FTGDMHGVRG
ADYACYRQAK RAGLKGTFRA FLSSRVQNVD SIVRLGDRDL PIVNVKGDVL FNSWKEMFNG
NGAYFSQNPR IYSFNGKNIL SDFTWPQKVV WHGSHTLGDR AMDTYCDAWH SGSSDRYGLG
SPLTGGRLLE QVRYSCDNKF ALLCIEVTSE QTKRRRRRRS LDEDEDEEEE DVDEEDESLL
TEAEYAEQLR QLFHAD
//
