ID A0A7M7N3S6_STRPU Unreviewed; 422 AA.
AC A0A7M7N3S6;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 {ECO:0008006|Google:ProtNLM};
OS Strongylocentrotus purpuratus (Purple sea urchin).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC Strongylocentrotus.
OX NCBI_TaxID=7668 {ECO:0000313|EnsemblMetazoa:XP_030830130, ECO:0000313|Proteomes:UP000007110};
RN [1] {ECO:0000313|Proteomes:UP000007110}
RP NUCLEOTIDE SEQUENCE.
RA Murali S., Liu Y., Vee V., English A., Wang M., Skinner E., Han Y.,
RA Muzny D.M., Worley K.C., Gibbs R.A.;
RT "Genome sequencing for Strongylocentrotus purpuratus.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:XP_030830130}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR RefSeq; XP_030830130.1; XM_030974270.1.
DR AlphaFoldDB; A0A7M7N3S6; -.
DR FunCoup; A0A7M7N3S6; 1354.
DR EnsemblMetazoa; XM_030974270; XP_030830130; LOC753175.
DR GeneID; 753175; -.
DR KEGG; spu:753175; -.
DR CTD; 11047; -.
DR InParanoid; A0A7M7N3S6; -.
DR OMA; SNQRHFF; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000007110; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IBA:GO_Central.
DR GO; GO:0061133; F:endopeptidase activator activity; IBA:GO_Central.
DR GO; GO:0070628; F:proteasome binding; IBA:GO_Central.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000007110}.
FT DOMAIN 15..128
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 295..407
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 124..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..151
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..252
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 43556 MW; CC11ABD0CD3D9D78 CRC64;
MSGALFGSSA TGGRPSSKNL VEFRAGKMEL KGTTVTSDKR KGLVYLHQPD DTLMHFCWKD
RTSGTVVDDL IIFPDDCEFK RVPQCTTGRV YILKFKSSAR KFFFWMQEPK TDKDDELCKK
VNDVLNNPPA PGSSGLGGGR GTGGLPADLG GLGSALGEGG LQSMLGNMDQ QQMMQLLSGG
GLGGLSPLGL QSMLGGARTG GASESTPSRT QSSARPATSS SSSVTPATTQ SSTPAARPST
TPAAVTPAAA AATPTSTASS AAAAAPGASP AAGQPAIQLR DLQSILSSMN LPGEAGAGQP
AVDLSQLMTS DAMTPILANQ EIQKKLIPFL PEGESLPKDP EQLRATLQSP QFQQALGMFT
AAFQSGQLGP LMAQFGLSSE ATDAANSGDI ESFSRALQGG SSSKDDKKDD KKDGDDEAMN
VD
//
