ID A0A7M7QEB7_NASVI Unreviewed; 425 AA.
AC A0A7M7QEB7;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 17.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
OS Nasonia vitripennis (Parasitic wasp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Proctotrupomorpha;
OC Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia.
OX NCBI_TaxID=7425 {ECO:0000313|EnsemblMetazoa:XP_031784122, ECO:0000313|Proteomes:UP000002358};
RN [1] {ECO:0000313|EnsemblMetazoa:XP_031784122}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR RefSeq; XP_031784122.1; XM_031928262.2.
DR AlphaFoldDB; A0A7M7QEB7; -.
DR SMR; A0A7M7QEB7; -.
DR FunCoup; A0A7M7QEB7; 1350.
DR EnsemblMetazoa; XM_031928262; XP_031784122; LOC116738459.
DR GeneID; 116738459; -.
DR KEGG; nvi:116738459; -.
DR CTD; 36545; -.
DR InParanoid; A0A7M7QEB7; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000002358; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000002358}.
FT DOMAIN 14..127
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 247..373
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 180..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..222
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 45785 MW; CF7998156750B8BF CRC64;
MSSNALFSNN GNRNVSKNLV EFKAGKMTMK GKMVYPDNRK GQLYVYQSDD SLMHFCWKDR
STGIVEDDLI IFPEDCEFKH VTQCKTGRVY LLKFKSSSRK FFFWLQDSKT DKDEEYCRKI
NEVLNNPPIP GSQRSSGANA EGDLQNLLNN MSQQQLMQLF GGVGQIGGLG SLLGTMNRPF
SSGSRISTTS SITPVTTAKS TTSSTPNSTA STTTTTTTSI GSEIPKPTGS DKSSSAKSAE
CTTSIVSDNR IRLSDLQSFL SGIPKPSHIE SEVQRGVASE LSSAIPAAIS TCESLEDLIS
TYLPAGDSLS TTLSSPQFSQ ALSLFWSALQ SGQAAPVVQQ FGLGSEAVNA ATTGNIHAFV
NALETEALNK SPASDAEAVD NSDMMNTKKS QEESTGKLKS DQPDSKTDTI NHKKDNDDDE
GMALD
//
