ID A0A7N2N5D2_QUELO Unreviewed; 349 AA.
AC A0A7N2N5D2;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 15.
DE RecName: Full=SPX domain-containing membrane protein {ECO:0008006|Google:ProtNLM};
OS Quercus lobata (Valley oak).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Fagaceae; Quercus.
OX NCBI_TaxID=97700 {ECO:0000313|EnsemblPlants:QL12p016890:mrna, ECO:0000313|Proteomes:UP000594261};
RN [1] {ECO:0000313|EnsemblPlants:QL12p016890:mrna, ECO:0000313|Proteomes:UP000594261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SW786 {ECO:0000313|EnsemblPlants:QL12p016890:mrna,
RC ECO:0000313|Proteomes:UP000594261};
RX PubMed=27621377; DOI=10.1534/g3.116.030411;
RA Sork V.L., Fitz-Gibbon S.T., Puiu D., Crepeau M., Gugger P.F., Sherman R.,
RA Stevens K., Langley C.H., Pellegrini M., Salzberg S.L.;
RT "First Draft Assembly and Annotation of the Genome of a California Endemic
RT Oak Quercus lobata Nee (Fagaceae).";
RL G3 (Bethesda) 6:3485-3495(2016).
RN [2] {ECO:0000313|EnsemblPlants:QL12p016890:mrna}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JAN-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; LRBV02000012; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A7N2N5D2; -.
DR EnsemblPlants; QL12p016890:mrna; QL12p016890:mrna; QL12p016890.
DR Gramene; QL12p016890:mrna; QL12p016890:mrna; QL12p016890.
DR InParanoid; A0A7N2N5D2; -.
DR OMA; QMSHEAN; -.
DR Proteomes; UP000594261; Chromosome 12.
DR GO; GO:0009705; C:plant-type vacuole membrane; IEA:TreeGrafter.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1905011; P:transmembrane phosphate ion transport from cytosol to vacuole; IEA:TreeGrafter.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR051068; MFS_Domain-Containing_Protein.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF75; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03105; SPX; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000594261};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..145
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 249..349
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 349 AA; 39914 MW; EAB655FC83F77C24 CRC64;
MVAFGKKLKE RQILEWQGYY INYKLMKKKV KQYAQQIEVG TQDRRHVLKD FSRMLDNQIE
KIVLFLLEQQ GLLASRLAKL DEQHNALQQQ PEISQICELR QAYRAVGQDL LKLLFFVEVN
AIGLRKILKK FDKRFGYRFT NDYVKTRANH PYSQLQQVFK HVGIGAVVGA ISRNLHELQD
RQGSYLSIYD QSALPLEDPV IDSIKAAVDR LTHSTNFLNF LAQHALIMQE EFPTPVEEQV
DDQNYHFLSL LLNLVNTFLY MVNTYIVVPT ADDYSLSLGA AATVCGIVIG AMAVAQVFSS
VYFSAWSNKT YFRPLVFSSV VLFVGNILYA LAYDFNSIAV LLIGRLFCG
//
