ID A0A7N5JF35_AILME Unreviewed; 1406 AA.
AC A0A7N5JF35;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSAMEP00000024433.1};
GN Name=SYCP2 {ECO:0000313|Ensembl:ENSAMEP00000024433.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000024433.1, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000024433.1, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000024433.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SYCP2 family.
CC {ECO:0000256|ARBA:ARBA00007960}.
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DR Ensembl; ENSAMET00000049360.1; ENSAMEP00000024433.1; ENSAMEG00000012412.2.
DR GeneTree; ENSGT00530000063859; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0000779; C:condensed chromosome, centromeric region; IEA:TreeGrafter.
DR GO; GO:0000800; C:lateral element; IEA:TreeGrafter.
DR GO; GO:0007143; P:female meiotic nuclear division; IEA:TreeGrafter.
DR GO; GO:0007140; P:male meiotic nuclear division; IEA:TreeGrafter.
DR InterPro; IPR024835; SYCP2-like.
DR InterPro; IPR041322; SYCP2_ARLD.
DR InterPro; IPR040560; SYCP2_SLD.
DR PANTHER; PTHR15607:SF12; SYNAPTONEMAL COMPLEX PROTEIN 2; 1.
DR PANTHER; PTHR15607; SYNAPTONEMAL COMPLEX PROTEIN-RELATED; 1.
DR Pfam; PF18581; SYCP2_ARLD; 1.
DR Pfam; PF18584; SYCP2_SLD; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 9..187
FT /note="Synaptonemal complex protein 2 armadillo-repeat-
FT like"
FT /evidence="ECO:0000259|Pfam:PF18581"
FT DOMAIN 278..389
FT /note="Synaptonemal complex protein 2 Spt16M-like"
FT /evidence="ECO:0000259|Pfam:PF18584"
FT REGION 442..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 959..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1073..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..556
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..694
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..715
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..772
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 970..979
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..998
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 999..1008
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1095
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1100..1111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1406 AA; 161413 MW; 7C526C2F21E00BDB CRC64;
MPIRPDLQQL EKCIDDALRK NDFKPLKTLL QIDICEDVKI KCSKQFFHKL DDLVCRELNK
KDIQAVSTIL VSFGRCGKNI TILGQGGLTA MIKQGLVQKM VAWFEKSKEI ILSRGNSKDE
TVINMIEDLF DLLMVIHDIN DEGKRQVVES FVPRICVLVI DSRVNICIQQ ETLKKMNAML
DKMPQDARKI LSNQEMLILM SSMGERILDA GDYDLQVGIV EALCRMTTEK QRQELAYQWF
SMDFIANAFK GIKDSEFETD CRVFLNLVNG MLGDKRRVFT FPCLSAFLGK YELQIPSDEK
LEEFWIDFNL GSQTLSFYIA GDNDDHQWEA VTVPEDKVQI YSIEVRESKK LLTIILKNIV
KISKREGKEL LLYFDASLEI TSVTQKIFGA NKYREFTRKQ GISVAKTSVH ILFDASGSQI
LVPESQISPM EEELITLKEK PNSQKEFAKP PKYIKNSNQG DRKNSQPEII TPSKRKMSEA
SMIVPGADRY TVRSPILLIN TSTPPRGRIK PPLQMMSSAE KPDIPKTSES GVGNAVSLTS
RPSEGRNGGD KTDQHIETAK VVEKTENKDI EFPNQNMNDL QDIVPDSQAV EKIDKPVLPG
VLDNICGNKM PSKWSCWTPV TNINLCDNQG AGTSSGDTFN QDVIVNKKLT KQKLSSSISE
DNSEETEKVQ YKKKTMQHNK IEKAEVGVCK RDTQQRPNHP KHSEQKNTEN TKQSDWRIES
ETTFKSVLLN KTVEESLIYR KKYVLSKDVN TAICDKSPSP KKKVRSHRKS GKRLTPELNS
WDLRQKKMRE KSKEKGFTDA AESLIKQINK RYKPKDDIKS TRKFKESLID SGFSNKSDLQ
LSKEKVQKKS YRQLKTSFVN VTSECPLNDV YNFNLNGADE PIIKLGIQEF QATATEACVD
NSIKLIGLRN QDELETSLKT KDKRIVTNPK KKNLFSDTDT EYRCDDSKTD VSWLKEPKSK
PQLIDYSRNK NMKKPKSGKS KPSLERGQPR SKVEENIHSR SKTMKLPKKQ QNAFSAETQK
DISKEWKNST LLKDAVRDNS LGLSPISLSG SPSPIEVMRC IEKIRERDFT QDYDRITKSL
SPSPKISSPE SLSSKYGVGD PKKSLKDSDK SLCARESCSP IPRSFLGSHS ASPLSLSSEG
REQIWLDMPR DSTHMSGPTR HLNRKRMYIE DNLSNADETE LEEEEKGRVY LLPKKLSKTE
DRDHHTYKVS GSVSPLSIND FSIHGESWES EILGLEVICE SLNTEFRRKF HIRQKLMDYF
TKLSWKTAQQ HLNTMNHQIQ EYRIKKLDKF QFIIIEELEN FEKDSQSLKE LEKEFVDFWE
KTFQKLNAYQ KREQQRLRLL KASLDKNVFY NTDYEDTVFT SEMCSMKENM KMLQDRLLKE
TQEEELLNVR RGLMSLFMAH ERNVRV
//
