ID   A0A7T6AQZ1_9BACT        Unreviewed;       811 AA.
AC   A0A7T6AQZ1;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   02-APR-2025, entry version 16.
DE   SubName: Full=Hydrogenase iron-sulfur subunit {ECO:0000313|EMBL:QQG65973.1};
GN   ORFNames=HP555_08880 {ECO:0000313|EMBL:QQG65973.1};
OS   Desulfobulbus oligotrophicus.
OC   Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfobulbia;
OC   Desulfobulbales; Desulfobulbaceae; Desulfobulbus.
OX   NCBI_TaxID=1909699 {ECO:0000313|EMBL:QQG65973.1, ECO:0000313|Proteomes:UP000596092};
RN   [1] {ECO:0000313|EMBL:QQG65973.1, ECO:0000313|Proteomes:UP000596092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Prop6 {ECO:0000313|EMBL:QQG65973.1,
RC   ECO:0000313|Proteomes:UP000596092};
RA   Podar M.;
RT   "Complete genome of Desulfobulbus oligotrophicus.";
RL   Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the HdrA family.
CC       {ECO:0000256|ARBA:ARBA00006561}.
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DR   EMBL; CP054140; QQG65973.1; -; Genomic_DNA.
DR   RefSeq; WP_199261652.1; NZ_CP054140.1.
DR   KEGG; dog:HP555_08880; -.
DR   Proteomes; UP000596092; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.20; -; 2.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR039650; HdrA-like.
DR   InterPro; IPR003813; MvhD/FlpD.
DR   NCBIfam; NF040770; hetero_SS_HdrA2; 1.
DR   PANTHER; PTHR43498:SF1; COB--COM HETERODISULFIDE REDUCTASE IRON-SULFUR SUBUNIT A; 1.
DR   PANTHER; PTHR43498; FERREDOXIN:COB-COM HETERODISULFIDE REDUCTASE SUBUNIT A; 1.
DR   Pfam; PF12831; FAD_oxidored; 1.
DR   Pfam; PF00037; Fer4; 1.
DR   Pfam; PF02662; FlpD; 1.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 3.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022827};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000596092};
KW   Selenium {ECO:0000313|EMBL:QQG65973.1};
KW   Selenocysteine {ECO:0000313|EMBL:QQG65973.1}.
FT   DOMAIN          252..279
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          593..622
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          625..654
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   NON_STD         212
FT                   /note="Selenocysteine"
FT                   /evidence="ECO:0000313|EMBL:QQG65973.1"
SQ   SEQUENCE   811 AA;  88533 MW;  7F4B63DEB2062C80 CRC64;
     MSKTSTANPA VKAAGPAEPR IGVYVCHCGL NIAQTVDCPK VAQEAADSSG VVVSKDIVYA
     CSEPGQQEIK QDIIDNGLDR VVIASCSPRL HETTFKKMAE AAGINPYMVD MANLREQCSW
     VHMKDRENAT VKAKTLVDMA ISRVRQLEPL YEDTLPLIQK SLVIGGGIAG IQAALDLADS
     GYDVVLVEKN PSIGGVMAQI DKTFPTMDCS IUILGPKMTD VGRHPRIQLL TLSEVVDVKG
     YVGNFKVKIL KKARYVDETS CTACGDCAQV CPVVRPDEFN VGLGSRKAIY SPFPQAVPSS
     YLINAKECLG PNPSVCSKCV EVCAKGCINF HMSDEEIIAE VGTIIVATGL QPYDPAEMDE
     YGYTRFDNVL TSLEFERLVN AGGPTKGELI RPSDRRLPGS VGFIQCVGSR SATKGGHYCS
     NICCMNTVKS TLILKEHYPD MEVKVFYIDI RAFGKGFEDL YTRSRRLGTQ YIRGLPGSVA
     ETDDGRLRVA VENGATGILE FHELDMLVLA QGMKPAPSTQ RLQEIMGLQL TSDGFYLEAH
     PKLQPVDAAT RGIFYAGCAE GPKDIKESVT QASAAAMRAV RLMHRGEITT EPITSFIITE
     KCKACGKCAE VCPYNAITVD VKAKKPAVVN AAACAGCGTC AAECRFDAIS MNHFTDAQIL
     GQVNSMLDTA PESKILAFAC NWCSYAGADY AGVSRLQYPA NVHLIRVMCS GRVDEKFIWE
     GFRRGAPIVL VSGCHIGDCH YIDANHWTAK RVERIRKKME KIGVRPERLQ LEWISAAEGI
     RFAETMRRME ELRRSVTAEE IAETQNILSK L
//