ID A0A7U7I8Y3_9GAMM Unreviewed; 639 AA.
AC A0A7U7I8Y3;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:CAD5107651.1};
GN ORFNames=PSEWESI4_01925 {ECO:0000313|EMBL:CAD5107651.1};
OS Zestomonas carbonaria.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Pseudomonadales; Pseudomonadaceae; Zestomonas.
OX NCBI_TaxID=2762745 {ECO:0000313|EMBL:CAD5107651.1, ECO:0000313|Proteomes:UP000583387};
RN [1] {ECO:0000313|EMBL:CAD5107651.1, ECO:0000313|Proteomes:UP000583387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP111764 {ECO:0000313|EMBL:CAD5107651.1};
RA Criscuolo A.;
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAD5107651.1}.
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DR EMBL; CAJFCI010000039; CAD5107651.1; -; Genomic_DNA.
DR RefSeq; WP_187670992.1; NZ_CAJFCI010000039.1.
DR AlphaFoldDB; A0A7U7I8Y3; -.
DR Proteomes; UP000583387; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF9; GTP-BINDING PROTEIN 1; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:CAD5107651.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000583387}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 639 AA; 69908 MW; 87D38A8448FFB1E7 CRC64;
MIVGTAGHID HGKTALLRAF TGIEGDRRPA ERARGITIDL GYLYADLGDG QLTGFIDVPG
HERFVHNMLA GACGIDLVLL VVAADDGVMP QTREHLAIVE LLGIPRALVA LSKCDRATPQ
RVDEVREQIA ALLANGPLAG APIHPLSSLT GEGVDALRAA LLEEAWVLEA RSAEGHFRLA
VDRAFSVSGA GVVATGTAFA GEVRIGDELL LSPSGQRVRV RGLHAQNRVA ETARAGQRVA
LNIAGERLSV ERIRRGDWLL APVLHAPTTR LDIDLHLLPG EARELAHWTP VHVHLGAQDV
TARVALLEGE RLAPGERGFA QLLLNAPAHA VHGDRLVLRD QSAQRTLGGG RVLDPFAPAR
DRRSPTRLTQ LAALRESSLE AALPVLLETA TNGLDPNVLE RQFNRAPSTW RLPEGVLEIT
TRLGARLFAT ERWEALGTEL LAALARFHTE QPDELGPDRD RLRRYALPQL ERPVFIALLE
QALAAGDIQA SGPWLHLPDH QVQLNAADEA LRTRLWPLLE AGAFDPPWVR DLARELKADE
AAVRLLLRKL ARLGLLHQVV KDLFYPDATI RQLAAQVLRL QDEEGVIRTA AFRDRIAIGR
KRGIQILEYF DRIGFTRRHG NERKVRTDSA LAMMNPGDP
//
