ID A0A7W3LTD2_ACTNM Unreviewed; 184 AA.
AC A0A7W3LTD2;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE SubName: Full=MerR family redox-sensitive transcriptional activator SoxR {ECO:0000313|EMBL:MBA8953915.1};
GN ORFNames=HNR61_005568 {ECO:0000313|EMBL:MBA8953915.1};
OS Actinomadura namibiensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=182080 {ECO:0000313|EMBL:MBA8953915.1, ECO:0000313|Proteomes:UP000572680};
RN [1] {ECO:0000313|EMBL:MBA8953915.1, ECO:0000313|Proteomes:UP000572680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44197 {ECO:0000313|EMBL:MBA8953915.1,
RC ECO:0000313|Proteomes:UP000572680};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBA8953915.1}.
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DR EMBL; JACJIA010000007; MBA8953915.1; -; Genomic_DNA.
DR RefSeq; WP_182846037.1; NZ_BAAALP010000043.1.
DR AlphaFoldDB; A0A7W3LTD2; -.
DR Proteomes; UP000572680; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd01110; HTH_SoxR; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR010211; Redox-sen_tscrpt-act_SoxR.
DR InterPro; IPR015358; Tscrpt_reg_MerR_DNA-bd.
DR NCBIfam; TIGR01950; SoxR; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR PANTHER; PTHR30204:SF0; REDOX-SENSITIVE TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF00376; MerR; 1.
DR Pfam; PF09278; MerR-DNA-bind; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000572680};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..78
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 184 AA; 20333 MW; E7601234C9D6A40E CRC64;
MTRLEYRVNE LTVGQLAERS GVAVSALHFY ESKGLITSRR TAGNQRRFSR DTLRRVAFIK
VSQRVGIPLA TIKEALETLP CERTPTAEDW ERLSEMWRAD LDERIEQLRK LRDSLDDCIG
CGCLSIRKCA LANPYDRLGD QGPGPRRLLV RHDPGEAADP APVAVGTGGD AGPDCCDPCA
PADR
//
