ID A0A7W7G3S0_9ACTN Unreviewed; 335 AA.
AC A0A7W7G3S0;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 08-OCT-2025, entry version 13.
DE SubName: Full=Cell wall-associated NlpC family hydrolase {ECO:0000313|EMBL:MBB4696578.1};
GN ORFNames=BKA14_006726 {ECO:0000313|EMBL:MBB4696578.1};
OS Paractinoplanes abujensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Paractinoplanes.
OX NCBI_TaxID=882441 {ECO:0000313|EMBL:MBB4696578.1, ECO:0000313|Proteomes:UP000542742};
RN [1] {ECO:0000313|EMBL:MBB4696578.1, ECO:0000313|Proteomes:UP000542742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45518 {ECO:0000313|EMBL:MBB4696578.1,
RC ECO:0000313|Proteomes:UP000542742};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC -!- SIMILARITY: Belongs to the transglycosylase Slt family.
CC {ECO:0000256|ARBA:ARBA00007734}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB4696578.1}.
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DR EMBL; JACHMF010000001; MBB4696578.1; -; Genomic_DNA.
DR RefSeq; WP_184954800.1; NZ_BOMC01000022.1.
DR AlphaFoldDB; A0A7W7G3S0; -.
DR Proteomes; UP000542742; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008933; F:peptidoglycan lytic transglycosylase activity; IEA:InterPro.
DR GO; GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
DR CDD; cd00254; LT-like; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000189; Transglyc_AS.
DR InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR PANTHER; PTHR37423:SF2; MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE C; 1.
DR PANTHER; PTHR37423; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF01464; SLT; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
DR PROSITE; PS00922; TRANSGLYCOSYLASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:MBB4696578.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000542742};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT DOMAIN 66..188
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
SQ SEQUENCE 335 AA; 34377 MW; D33C5990899989AD CRC64;
MIGVTGVLNR IQELQGQLGL TPVNPAPGAT GATGTVSTTG PGGTTTFASA LASATGQGGS
MRLNNQATGQ NVVDAAKKYL GTPYVFGSTD PDKGLDCSAL VQRAYSDLGI KLPRLSHQQA
KAGEPVANLA QAKPGDILAF DSPVDHVAIY LGDNKMIAAP KPGDHVKIQS VYEKPTHIRR
VVSDFPVTPQ NAVSAIRPAS LQGTGALAGV PYADLFVQAG NRYGVSPKLL AAVAKVESGY
DPKAVSKAGA QGLMQLMPST ARGLGVKDSF DPAQAINGGA KLLARNLREF KSLPLALAAY
NAGGGAVHRY GGIPPFSETQ KYVPKVQKAL AALGG
//
