ID A0A7W7VVJ9_KITKI Unreviewed; 562 AA.
AC A0A7W7VVJ9;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 08-OCT-2025, entry version 14.
DE SubName: Full=Cell wall-associated NlpC family hydrolase {ECO:0000313|EMBL:MBB4923580.1};
GN ORFNames=FHR34_002573 {ECO:0000313|EMBL:MBB4923580.1};
OS Kitasatospora kifunensis (Streptomyces kifunensis).
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=58351 {ECO:0000313|EMBL:MBB4923580.1, ECO:0000313|Proteomes:UP000540506};
RN [1] {ECO:0000313|EMBL:MBB4923580.1, ECO:0000313|Proteomes:UP000540506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41654 {ECO:0000313|EMBL:MBB4923580.1,
RC ECO:0000313|Proteomes:UP000540506};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB4923580.1}.
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DR EMBL; JACHJV010000001; MBB4923580.1; -; Genomic_DNA.
DR RefSeq; WP_184935660.1; NZ_JACHJV010000001.1.
DR AlphaFoldDB; A0A7W7VVJ9; -.
DR Proteomes; UP000540506; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR051794; PG_Endopeptidase_C40.
DR PANTHER; PTHR47359:SF3; NLP_P60 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47359; PEPTIDOGLYCAN DL-ENDOPEPTIDASE CWLO; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:MBB4923580.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000540506};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT SIGNAL 1..42
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 43..562
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030736036"
FT DOMAIN 277..398
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
FT REGION 42..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..78
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..452
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..474
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..562
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 56086 MW; 307B8676D88FF153 CRC64;
MRAVRREQLV GGQPWLRAAL RCGAVLAMAA LALPLAGQTA FAATEPPPST ASPSTASPST
AAAAGGPAGA PASPDADPLA QAKATLGPLL DKIHLLYQNA ETATEQYNAT VQQLADRQST
VAAVNAKLDA QQKLVDQSID VASELASEQY RNGDLSGFGE LLLTNDPYQA AHLAALLSAA
SRSQAAFIAQ LKSDQAALTQ LKKQSGDAVD SSKALLAQQD QNKADIARQL ATVEQLVSSL
TGAQQNELQQ LEQNQVDQAQ LAFLASGALG QGERTPSAAG RQAVAFALAQ LGKPYLWGAI
GPDTYDCSGL TSQAWLHAGV QIPRTSQDQW AQLQHVPLNQ LRPGDLVVYY ESAEHIAMYI
GGGLVVQAPH AGTVVRVSPI GMAPILGAVR PDPQNASDDK GGAWKVPATL QDAETITPIA
PGQGTAPGLP SEPPLPPQLP VVPIIPPTPP ASPSAGSKPA PAGPAPAGPS PAGPSPSGAS
PSGATSSPSG SGSAAPSGSA NPSAPPSGSA SPTGSGSASP TSSPSGSVSG SPAPSGTPSA
SPSGTAPATG SPSPSSSGNP SH
//
