ID A0A7X2L4B1_9BACL Unreviewed; 370 AA.
AC A0A7X2L4B1;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE SubName: Full=Amidohydrolase/deacetylase family metallohydrolase {ECO:0000313|EMBL:MRN56123.1};
DE EC=3.5.2.3 {ECO:0000313|EMBL:MRN56123.1};
GN ORFNames=GJB61_24420 {ECO:0000313|EMBL:MRN56123.1};
OS Paenibacillus monticola.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Paenibacillus.
OX NCBI_TaxID=2666075 {ECO:0000313|EMBL:MRN56123.1, ECO:0000313|Proteomes:UP000463051};
RN [1] {ECO:0000313|EMBL:MRN56123.1, ECO:0000313|Proteomes:UP000463051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC-T2 {ECO:0000313|EMBL:MRN56123.1,
RC ECO:0000313|Proteomes:UP000463051};
RA Zhao Q., Li H.-P., Zhang J.-L.;
RT "Paenibacillus monticola sp. nov., a novel PGPR strain isolated from
RT mountain sample in China.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MRN56123.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; WJXB01000012; MRN56123.1; -; Genomic_DNA.
DR RefSeq; WP_154121622.1; NZ_WJXB01000012.1.
DR AlphaFoldDB; A0A7X2L4B1; -.
DR Proteomes; UP000463051; Unassembled WGS sequence.
DR GO; GO:0019213; F:deacetylase activity; IEA:InterPro.
DR GO; GO:0004151; F:dihydroorotase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR020043; Deacetylase_Atu3266-like.
DR InterPro; IPR047601; EF_0837-like.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR03583; EF_0837; 1.
DR NCBIfam; NF006689; PRK09237.1; 1.
DR PANTHER; PTHR42717; DIHYDROOROTASE-RELATED; 1.
DR PANTHER; PTHR42717:SF1; IMIDAZOLONEPROPIONASE AND RELATED AMIDOHYDROLASES; 1.
DR Pfam; PF22647; EF_0837-like_N; 1.
DR PIRSF; PIRSF039004; ADE_EF_0837; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:MRN56123.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR039004-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000463051};
KW Zinc {ECO:0000256|PIRSR:PIRSR039004-1}.
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 59
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 151
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /note="via carbamate group"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 151
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /note="via carbamate group"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 184
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 207
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT BINDING 267
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-1"
FT SITE 153
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-3"
FT MOD_RES 151
FT /note="N6-carboxylysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR039004-2"
SQ SEQUENCE 370 AA; 40822 MW; E0D8392B59E351DC CRC64;
MNERFVLRYV KLMSGQEIDI VIENKKIAEI TKAGEGSGQQ EWNGSGAYVS SGWIDMHVHA
FPDFDPYGDE IDEIGVKQGV TTIVDAGSCG ADRIADLVYD SSRAKTNVLA FLNISRIGLL
RIDELSRLEW MDREKVRQSV RAYGDVIVGL KARISRSVVG ENQIEPLCIA RELSRETGLP
LMVHIGSAPP DIREVMPLLE RKDIVTHYLN GKENNLFDAD GKPQQVLTDA IERGVHLDVG
HGTASFSFKV AEAAKRHNIA FNTISTDIYR GNRLNGPVYS MASVLSKFLC LGYSLEEIIA
AVTTHAADWL GKPELGRIQV GDIANLTLFT LHNEPTVLTD SEGEQRVTDR VIQVKGVVAS
GEFIECEIRA
//
