ID A0A7X2M118_9BACI Unreviewed; 140 AA.
AC A0A7X2M118;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 18-JUN-2025, entry version 17.
DE SubName: Full=Na(+)/H(+) antiporter subunit B {ECO:0000313|EMBL:MRX73579.1};
GN ORFNames=GJU40_15650 {ECO:0000313|EMBL:MRX73579.1};
OS Metabacillus lacus.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Metabacillus.
OX NCBI_TaxID=1983721 {ECO:0000313|EMBL:MRX73579.1, ECO:0000313|Proteomes:UP000448867};
RN [1] {ECO:0000313|EMBL:MRX73579.1, ECO:0000313|Proteomes:UP000448867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 33946 {ECO:0000313|EMBL:MRX73579.1,
RC ECO:0000313|Proteomes:UP000448867};
RA Allen C.J., Newman J.D.;
RT "Bacillus lacus genome.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000256|ARBA:ARBA00009425}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MRX73579.1}.
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DR EMBL; WKKI01000038; MRX73579.1; -; Genomic_DNA.
DR RefSeq; WP_343031581.1; NZ_WKKI01000038.1.
DR AlphaFoldDB; A0A7X2M118; -.
DR Proteomes; UP000448867; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR050622; CPA3_antiporter_subunitB.
DR InterPro; IPR005281; CPA3_sub_B.
DR InterPro; IPR007182; MnhB.
DR NCBIfam; TIGR00943; 2a6301s02; 1.
DR NCBIfam; NF009223; PRK12573.1; 1.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B; 1.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000448867};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022449}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..131
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 140 AA; 15110 MW; 1FA6C5E7F166D4B6 CRC64;
MKTNDVIFQT TTKVVLFIIV MFSIFLFFAG HHNPGGGFIG GLMTSSAIVL LLLAYDIKTV
KKILPINFLT LTAVGLMIAV LTGVGSFLFG APFLSHTFDY FELPLLGETE LATAVLFDIG
VYLVVVGVTM TIIQTIGESE
//
