ID A0A7X6L0G9_9NOCA Unreviewed; 217 AA.
AC A0A7X6L0G9;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 08-OCT-2025, entry version 19.
DE SubName: Full=TetR/AcrR family transcriptional regulator {ECO:0000313|EMBL:NKY25458.1};
GN ORFNames=HGB38_04305 {ECO:0000313|EMBL:NKY25458.1};
OS Nocardia gamkensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Nocardiaceae; Nocardia.
OX NCBI_TaxID=352869 {ECO:0000313|EMBL:NKY25458.1, ECO:0000313|Proteomes:UP000540698};
RN [1] {ECO:0000313|EMBL:NKY25458.1, ECO:0000313|Proteomes:UP000540698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44956 {ECO:0000313|EMBL:NKY25458.1,
RC ECO:0000313|Proteomes:UP000540698};
RA Nicholson A.C.;
RT "MicrobeNet Type strains.";
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NKY25458.1}.
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DR EMBL; JAAXOS010000002; NKY25458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7X6L0G9; -.
DR Proteomes; UP000540698; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:TreeGrafter.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:TreeGrafter.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-ARBA.
DR FunFam; 1.10.10.60:FF:000141; TetR family transcriptional regulator; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR054129; DesT_TetR_C.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR050109; HTH-type_TetR-like_transc_reg.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF227; TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)-RELATED; 1.
DR Pfam; PF21943; TetR_C_46; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000540698};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..77
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 40..59
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 217 AA; 24149 MW; AA3EE00B5DF8E7B3 CRC64;
MSSGESHRVS RPRMTGTQRR QQLIEIGRAL FAERGYDATS IEEIAQRAQV SKPVVYEHFG
GKEGLYAVVV DREMSMLLDM ITSSLTQNRS RIRLEQVALA LLTYIEERTD GFRILVRDQP
AAAAEGRYSS LLNEATNQVA HILAGDFARR GFDTSLSTLY AQALVGQVAT AATWWLDERQ
PSKEVVAAHL VNLCWNGLSH LEAEPQLSSE WRASAGE
//
