ID A0A7Y0B3B4_9ACTN Unreviewed; 308 AA.
AC A0A7Y0B3B4;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 05-FEB-2025, entry version 12.
DE SubName: Full=Copper resistance protein CopD {ECO:0000313|EMBL:NML78363.1};
GN ORFNames=HHL19_06725 {ECO:0000313|EMBL:NML78363.1};
OS Streptomyces sp. R302.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2728844 {ECO:0000313|EMBL:NML78363.1, ECO:0000313|Proteomes:UP000541839};
RN [1] {ECO:0000313|EMBL:NML78363.1, ECO:0000313|Proteomes:UP000541839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R302 {ECO:0000313|EMBL:NML78363.1,
RC ECO:0000313|Proteomes:UP000541839};
RA Dahal R.H.;
RT "Streptomyces sp. R302 sp. nov., isolated from soil.";
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NML78363.1}.
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DR EMBL; JABBGE010000002; NML78363.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7Y0B3B4; -.
DR Proteomes; UP000541839; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF05425; CopD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000541839};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 207..297
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
SQ SEQUENCE 308 AA; 31052 MW; 4093CC1C414435E5 CRC64;
MTLPGPFGTP GRRGAVALVA AALGVLGVLA VVGLGAGLAR TGTGELRIPA AGTTTLLRLL
LLTGLAVTVG ELAGRRIAGQ GPLPRPLAVP GALLAAAAAT GLLLLLAAVS GLSLPVVYGL
REGRLLLATA NACLLAAVCA ASRRPGLAAL PLAAAIVAEA LRAHPESPGF GVGTGLTVVH
LTAASLWTGT LLYVLRVLRA RDEGGRAVLL RYARMAACVY AALAVTGTVS TLRRLPLEAA
FTTAYGRVLL VKLALFGAAS LLALAARSRL RSDADATPPA RVELAVLAVI VALSSLLTVV
PDPHWLLF
//
