ID A0A7Z0WN89_9PSEU Unreviewed; 573 AA.
AC A0A7Z0WN89;
DT 02-JUN-2021, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 1.
DT 28-JAN-2026, entry version 20.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=BLA60_15955 {ECO:0000313|EMBL:OLF10662.1};
OS Actinophytocola xinjiangensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae.
OX NCBI_TaxID=485602 {ECO:0000313|EMBL:OLF10662.1, ECO:0000313|Proteomes:UP000185696};
RN [1] {ECO:0000313|EMBL:OLF10662.1, ECO:0000313|Proteomes:UP000185696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.4663 {ECO:0000313|EMBL:OLF10662.1,
RC ECO:0000313|Proteomes:UP000185696};
RA Wang W., Yuan L.;
RT "The draft genome sequence of Actinophytocola xinjiangensis.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLF10662.1}.
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DR EMBL; MSIF01000006; OLF10662.1; -; Genomic_DNA.
DR RefSeq; WP_075133651.1; NZ_MSIF01000006.1.
DR AlphaFoldDB; A0A7Z0WN89; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000185696; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:OLF10662.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000185696}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 573 AA; 59873 MW; 9CCEF613DA451A5B CRC64;
MHVIATAGHV DHGKSTLVRA LTGMEPDRLA EERRRGLTID LGFAWTELDD QVLAFVDVPG
HERFVPNMLA GAGPVPAAMF VVAADEGWAE QSAEHLTALD AFGVRHGLLV VTKSDRADPA
AATDLAREQL AGTGLAGVRA VAVSGRTGAG LPELRRELLA LTAALPVPDR AADVRLWVDR
AFTIRGAGTV VTGTLGAGTL RVGDELDLGG RRVVVRGLQA LGRPREEVAA VARVAVNLRG
VDRDEVRRGD ALLTPSAFPV TGEIDVRLRG DSAQRRSLVL HVGAAAVPCR VRPLGTDTAR
LALASGLALR AGDIGLLRDP GEHRILAAVE VLDPCPPPLS GRGAARQRVV DLADPAAAYL
RRRGVVPLAQ LRVLGHPPVG VAVGDLAVDE TLLGELPGRV ADRFRAWSAG HPIAAGLPIE
ALRREFGVPD PVLRQAIRET SLTVHNGLVR AGDAVAGLPA ELAEAVAAVE ARLDGAPFTA
PEAADLSALG LGPRQLAAAE RAGRLVRLAG SVVLAADAPD RAATVLAGIA APFTVSDARR
ALGTTRRVAV PLLELLDARR VTRRHADGTR TLR
//
