ID A0A810NB61_9ACTN Unreviewed; 676 AA.
AC A0A810NB61;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 08-OCT-2025, entry version 17.
DE SubName: Full=Rhamnulose-1-phosphate aldolase {ECO:0000313|EMBL:BCJ69329.1};
GN Name=rhaD {ECO:0000313|EMBL:BCJ69329.1};
GN ORFNames=Prubr_63500 {ECO:0000313|EMBL:BCJ69329.1};
OS Polymorphospora rubra.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Polymorphospora.
OX NCBI_TaxID=338584 {ECO:0000313|EMBL:BCJ69329.1, ECO:0000313|Proteomes:UP000680866};
RN [1] {ECO:0000313|EMBL:BCJ69329.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 101157 {ECO:0000313|EMBL:BCJ69329.1};
RA Komaki H., Tamura T.;
RT "Whole genome shotgun sequence of Polymorphospora rubra NBRC 101157.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; AP023359; BCJ69329.1; -; Genomic_DNA.
DR RefSeq; WP_212818538.1; NZ_AP023359.1.
DR AlphaFoldDB; A0A810NB61; -.
DR KEGG; pry:Prubr_63500; -.
DR Proteomes; UP000680866; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR FunFam; 3.40.50.720:FF:000084; Short-chain dehydrogenase reductase; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001303; Aldolase_II/adducin_N.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR013454; Bifunc_RhaD/ADH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR NCBIfam; NF006188; PRK08324.1-1; 1.
DR NCBIfam; NF006189; PRK08324.1-3; 1.
DR NCBIfam; TIGR02632; RhaD_aldol-ADH; 1.
DR PANTHER; PTHR43669; 5-KETO-D-GLUCONATE 5-REDUCTASE; 1.
DR PANTHER; PTHR43669:SF8; SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE-RELATED; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR Pfam; PF00596; Aldolase_II; 1.
DR PRINTS; PR00081; GDHRDH.
DR SMART; SM01007; Aldolase_II; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000680866}.
FT DOMAIN 8..210
FT /note="Class II aldolase/adducin N-terminal"
FT /evidence="ECO:0000259|SMART:SM01007"
FT REGION 12..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 676 AA; 71592 MW; C4401394BA7E3AF6 CRC64;
MTNPAVRDLL DRSNRLGADP ANTNYAGGNT STKGVETDPV TGEPTDLLWV KGSGGDLGTL
TEHGLAALRL DRLRCLVDVY PGVEREDEMV AAFDYCLHGR GGAAPSIDTA MHGLVDVTHV
DHLHPDSGIA IATAADGPEL TRKIFGDRVL WVPWRRPGFQ LGLDIAAAQR ANPQAIGVIL
GGHGITAWGA TSDDCEANSR EIIVTAARYI AEHGRPEPFG KLVYEPLPEP ERQARAAALL
PVLRGLASTD RAQVGHYTDS DVVLDFVGRE RMAELSALGT SCPDHFLRTK VRPMVLDLPP
TAGLAETVAR LRELHAVYRA DYRAYYERYA EADSPALRGA DPAIVLVPGV GMFSFGANKQ
TARVAGEFYV NAVNVMRGAE AVSAYAPIDE AEKFRIEYWA LEEAKLQRMP KPRPLSTRIA
LVTGAGSGIG RAIAHRIAAE GACVVVTDRD AVAARTVAAE IGGPDAAVAV PLDVTDEEQV
AAAVRAAVLA FGGVDLVVNN AGLSLSKSLL DTTARDWDRQ HDVMAKGSFL VSREVARVLV
AQGMGGDIVY IASKNAVFAG PNNVAYGAAK ADQAHQVRLL AAELGAHGVR VNGVNPDGVV
RGSGIFAGGW GADRAAVYGV PEEKLGEFYA QRTLLKREVL PEHVANAVFA LTAGDLSHTT
GLHIPVDAGV AAAFLR
//
