ID A0A812EZH4_ACAPH Unreviewed; 352 AA.
AC A0A812EZH4;
DT 29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 1.
DT 18-JUN-2025, entry version 12.
DE SubName: Full=RPN13 {ECO:0000313|EMBL:CAE1331429.1};
GN ORFNames=SPHA_80610 {ECO:0000313|EMBL:CAE1331429.1};
OS Acanthosepion pharaonis (Pharaoh cuttlefish) (Sepia pharaonis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Decapodiformes; Sepiida; Sepiina; Sepiidae; Acanthosepion.
OX NCBI_TaxID=158019 {ECO:0000313|EMBL:CAE1331429.1, ECO:0000313|Proteomes:UP000597762};
RN [1] {ECO:0000313|EMBL:CAE1331429.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Farmed {ECO:0000313|EMBL:CAE1331429.1};
RA Li R., Bekaert M.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAE1331429.1}.
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DR EMBL; CAHIKZ030005604; CAE1331429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A812EZH4; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000597762; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000597762}.
FT DOMAIN 1..75
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 239..351
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 123..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..207
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 37972 MW; 0378ED54CAEA3EF9 CRC64;
MHFCWKDRTS GQVEDDLIIF PDDIEFKRIP QCTTGRCYVL KFKSSVRRFF FWMQEPKSEK
DDELCRKVNE YLNNPPNPSV NRNNVSDLPG LGESDLHNIL GNMSQQQLMQ LLGGMGMPAQ
NNLNLSTILG RPGNSSTSGS DSSTRLQSSL GTRNSSTSSD SLSSAARPAT ATASLTSQTT
DSTASNSSTS TASASSGAVA SGSSSSSSGG GGSRPGDTPW QQIQLSDLQN ILSNMQVPGD
KPQDTLELSQ VLKPDDIIPI LANADIQKHL MEHLPEGEML PRTEEELRNT VKSPQFQQAL
QSFSAALRSR ELGPLMTQFG LGDDVAKAAA EGDLEAFVKA LQEAQKKKAE GK
//
