ID   A0A812WF27_9DINO        Unreviewed;       552 AA.
AC   A0A812WF27;
DT   29-SEP-2021, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 1.
DT   05-FEB-2025, entry version 11.
DE   SubName: Full=FAHD1 protein {ECO:0000313|EMBL:CAE7668977.1};
DE   Flags: Fragment;
GN   Name=FAHD1 {ECO:0000313|EMBL:CAE7668977.1};
GN   ORFNames=SLIN2456_LOCUS23760 {ECO:0000313|EMBL:CAE7668977.1};
OS   Symbiodinium sp. CCMP2456.
OC   Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC   Symbiodinium.
OX   NCBI_TaxID=1519616 {ECO:0000313|EMBL:CAE7668977.1, ECO:0000313|Proteomes:UP000639591};
RN   [1] {ECO:0000313|EMBL:CAE7668977.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Dougan E. K., Rhodes N., Thang M., Chan C.;
RL   Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CAE7668977.1}.
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DR   EMBL; CAJNDV010032767; CAE7668977.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A812WF27; -.
DR   OrthoDB; 411064at2759; -.
DR   Proteomes; UP000639591; Unassembled WGS sequence.
DR   GO; GO:0018773; F:acetylpyruvate hydrolase activity; IEA:TreeGrafter.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR   Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR   PANTHER; PTHR11820:SF7; ACYLPYRUVASE FAHD1, MITOCHONDRIAL; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   Pfam; PF01557; FAA_hydrolase; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF56529; FAH; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000639591}.
FT   DOMAIN          33..130
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
FT   DOMAIN          164..284
FT                   /note="Ketopantoate reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08546"
FT   DOMAIN          328..504
FT                   /note="Fumarylacetoacetase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01557"
FT   NON_TER         552
FT                   /evidence="ECO:0000313|EMBL:CAE7668977.1"
SQ   SEQUENCE   552 AA;  60105 MW;  810ED590D3B78F9B CRC64;
     MVRKETLRVL SGDGVRVRSI CGDVHIPRKD LDQVMNTEAL DKESKFEADV IVLACKAWEV
     ERCLKMCQPW CGANTLVLPL QNGVDAFGTV RSIVTSWGKG RPLVGWCNIV AAIQEPGLIK
     HWAANPPCIY CGEFEGAPTS RTKHMESVLA SCEGMAVSLE HDALSKCWEK FSFICSTTAV
     QATAGPSATQ DLIPQVPELE QMWRSAMEEI IAIAKKSGID YQQSWMEKRI PVLRDAIGAT
     TSCSRDLWAG RHSELEDLLG SVHRMGQEKG VPTPVISTCL RALTVRDQLA RRATTLPIYP
     MLEGQKILGT ICNHQGQQLP ADRTLAQKKA AEYLRPEWFV CPMTSAIATG GQCEVPEGVQ
     MLWEAELGVV ISHSCENLSP HEALDYVGGY CMVLDLTGGN LGFESMKYGH SWTRNKCQNT
     FKPVGAFIPA SVLPKPESSR IICRVNGKTV AEDEISKMKF TIAQQVADAS ELTPLRRGDI
     LLTGAGSLGP LAIGDLVEGS IEGLDAKYTV SATLAGEVPK CSPAPLATIL ESSLLQLMLQ
     RTMCAAYAQE AE
//